| Lange's test | An obsolete, non-specific test for altered proteins in spinal fluid. As originally used by Lange in 1912, the test was thought to be specific for neurosyphilis; however, this proved to be incorrect. Dilutions of spinal fluid are made in saline and to these a colloidal gold solution is added; if altered proteins are present, there is a colour change or precipitate formed. at present, its chief use is to demonstrate cerebrospinal fluid protein abnormalities in multiple sclerosis. Synonym: gold sol test, Zsigmondy's test. (05 Mar 2000) |
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| Cornelia de Lange syndrome | <syndrome> A congenital anomaly characterised by impaired development, mental retardation, characteristic facies with snyophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym: Amsterdam syndrome, Cornelia de Lange syndrome. (05 Mar 2000) |
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| de Lange | Cornelia, Dutch paediatrician, 1871-1950. See: de Lange syndrome. (05 Mar 2000) |
| de lange's syndrome | <syndrome> A congenital syndrome in which severe mental retardation is associated with many abnormalities, including short stature (amsterdam dwarf), brachycephaly, low-set ears, webbed neck, carp mouth, depressed bridge of the nose with the end tilted up and forward-directed nostrils, bushy eyebrows meeting at the midline, unruly coarse hair growing low on the forehead and neck, and flat spadelike hands with short tapering fingers. Called also brachmann-de lange or cornelia delange syndrome and typus degenerativus amstelodamensis. (12 Dec 1998) |
| de Lange syndrome | <syndrome> A congenital anomaly characterised by impaired development, mental retardation, characteristic facies with snyophrys and hairline well down on forehead, depressed bridge of nose with uptilted tip of nose, small head with low-set ears, and flat spadelike hands with simian crease and short tapering fingers. Synonym: Amsterdam syndrome, Cornelia de Lange syndrome. (05 Mar 2000) |
| James-Lange theory | That bodily changes, such as tachycardia or sweating, precede rather than follow the conscious perception of an emotion and by themselves evoke the emotional feeling. (05 Mar 2000) |
| Jervell and Lange-Nielsen syndrome | <syndrome> A prolonged Q-T interval recorded in the electrocardiogram of certain congenitally deaf children subject to attacks of unconsciousness resulting from Adams-Stokes seizures and ventricular fibrillation; autosomal recessive inheritance. Synonym: surdocardiac syndrome. (05 Mar 2000) |
| Lange, Carl F | <person> German biochemist, *1883. See: Lange's solution, Lange's test. (05 Mar 2000) |
| Lange, Carl G | <person> Danish psychologist, 1834-1900. See: James-Lange theory. (05 Mar 2000) |
| Lange-Nielsen, F | <person> 20th century Norwegian cardiologist. See: Jervell and Lange-Nielsen syndrome. (05 Mar 2000) |
| Lange's solution | A colloidal gold solution used to demonstrate protein abnormalities in spinal fluid. See: Lange's test. (05 Mar 2000) |
| Abbe test plate | <equipment> A long, wedge-shaped coverslip about 0.20 mm thick at one end and 0.10 to 0.12 mm at the other end coated chemically with a silver film on which are ruled horizontal lines. at each variation in thickness of 0.01 mm there are vertical lines. By means of oblique illumination and by focusing on different portions of the plate, it is possible to determine the optimum coverslip thickness for any objective and also, for microscopes with drawtubes, the tube length for best objective performance. The approximate freedom from spherical and chromatic aberrations can also be estimated. Small isolated bits of silver near the edges of the lines form good objects for the star test (05 Aug 1998) |
| acetone test | A test for ketonuria; the suspected urine is shaken up with a few drops of sodium nitroprusside, and strong ammonia water is then gently poured over the mixture; if acetone is present, a magenta ring forms at the line of contact; tablets containing sodium nitroprusside and alkali are now more commonly used. (05 Mar 2000) |
| achievement test | A standardised test used to measure acquired learning, e.g., competence in a specific subject area such as reading or arithmetic, in contrast to an intelligence test which is a useful index of potential ability or learning. (05 Mar 2000) |
| acidified serum test | Lysis of the patient's red cells in acidified fresh serum, specific for paroxysmal nocturnal haemoglobinuria. Synonym: Ham's test. (05 Mar 2000) |
| acid loading test | <nephrology> This is a test used in the diagnosis of renal tubular acidosis. The patient takes ammonium chloride capsules for 3 days to acidify the blood (lower blood pH). A sample of the urine and the blood is then collected and the results are interpreted. (27 Sep 1997) |