| Kallmann | Franz Josef, U.S. Medical geneticist and psychiatrist, 1897-1965. See: Kallmann's syndrome. (05 Mar 2000) |
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| kallmann syndrome | <syndrome> Congenital and familial disorder characterised by hypogonadotropic hypogonadism, eunuchoidal features, and anosmia or hyposmia. It is caused by a defect in the synthesis and/or release of lhrh (luteinizing hormone-releasing hormone; gonadorelin) from the hypothalamus as a result of faulty embryonic neuronal migration. The gene responsible for this is found in the region xp22.3 on the short arm of the x chromosome. There is a homolog on the y chromosome. The syndrome is more prevalent in males by a ratio of three to one. (12 Dec 1998) |
| Kallmann's syndrome | Failure of sexual development secondary to inadequate secretion of pituitary gonadotropins, associated with anosmia due to agenesis of the olfactory lobes of the brain; probably X-linked inheritance. Synonym: Kallmann's syndrome. (05 Mar 2000) |