| leukemia | <haematology> An acute or chronic disease of unknown cause in man and other warm blooded animals that involves the blood forming organs, is characterised by an abnormal increase in the number of leucocytes in the tissues of the body with or without a corresponding increase of those in the circulating blood and is classified according of the type leucocyte most prominently involved. (18 Nov 1997) |
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| antigens, differentiation, myelomonocytic | Surface antigens expressed on myeloid cells of the granulocyte-monocyte-histiocyte series during differentiation. Analysis of their reactivity in normal and malignant myelomonocytic cells is useful in identifying and classifying human leukaemias and lymphomas. (12 Dec 1998) |
| chronic myelomonocytic leukaemia | <haematology> A form of myelodysplasia characterised by an increase in the number of circulating white blood cells of the monocyte type. Acronym: CMML Origin: Gr. Haima = blood (12 Jan 1998) |
| myelomonocytic leukaemia | A variant of granulocytic leukaemia with monocytosis in the peripheral blood. Synonym: Naegeli type of monocytic leukaemia. (05 Mar 2000) |
| arthritis, juvenile rheumatoid | Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (still's disease, juvenile-onset) polyarticular-onset, and pauciarticular-onset. Adult-onset cases of still's disease (still's disease, adult-onset) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent. (12 Dec 1998) |
| benign juvenile melanoma | A benign, slightly pigmented or red superficial small skin tumour composed of spindle-shaped, epithelioid, and multinucleated cells that may appear atypical; most common in children, but also appearing in adults. Synonym: benign juvenile melanoma, epithelioid cell nevus, spindle cell nevus. (05 Mar 2000) |
| rheumatoid arthritis, systemic-onset juvenile | Also known as systemic-onset juvenile chronic arthritis. Still's disease presents with systemic (bodywide) illness including high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis may not be immediately apparent but it does appear and may persist after the systemic symptoms are gone. (12 Dec 1998) |
| periodontitis, juvenile | Localised periodontitis in teenagers and young adults. The onset is during the circumpubertal period but the diagnosis can be made beyond puberty. Lesions are confined predominantly to the first permanent molars or incisors and the distribution of lesions is usually symmetrical. The gingiva may appear normal. The lesions are highly active immediately following puberty but later destruction may slow or cease spontaneously. The disease is four times more prevalent in females than males and more prevalent in african americans than in other races or ethnic groups. (12 Dec 1998) |
| xanthogranuloma, juvenile | Benign disorder of infants and children characterised by multiple nodules with lipid-laden, non-langerhans-cell histiocytes. (12 Dec 1998) |
| systemic-onset juvenile chronic arthritis | See: Systemic-onset juvenile rheumatoid arthritis (still's disease). (12 Dec 1998) |
| systemic-onset juvenile rheumatoid arthritis | <rheumatology> A form of joint disease, arthritis, that presents with systemic upset. Clinical signs: high intermittent fever, a salmon-coloured skin rash, swollen lymph glands, enlargement of the liver and spleen, and inflammation of the lungs (pleuritis) and around the heart (pericarditis). The arthritis itself may not be immediately apparent but once apparent, it may persist after the systemic symptoms have resolved. Synonym: Still's disease. (03 Jul 1999) |
| juvenile | Pertaining to youth or childhood, young or immature. (18 Nov 1997) |
| juvenile absence epilepsy | A generalised epilepsy syndrome with onset around puberty, characterised by absence seizures and generalised tonic-clonic seizures. EEG often shows a greater than 3 Hz generalised spike wave pattern. (05 Mar 2000) |
| juvenile angiofibroma | <oncology, tumour> A benign tumour of the posterior nasopharynx that is most common in adolescent boys. Symptoms repeated epistaxis, nasal congestion, nasal discharge and hearing loss. A skull X-ray or a CT scan of the head can confirm the presence of an angiofibroma. Treatment may include the surgical removal of the lesion if it is enlarging or blocking the airway. (27 Sep 1997) |
| juvenile arrhythmia | <cardiology, physiology> An increase in heart rate during inspiration. A normal physiologic response, more pronounced in children. (27 Sep 1997) |