| 영문 | aging, senescence | 한글 | 노화, 늙음 |
|---|---|---|---|
| 설명 | 나이 먹는다는 의미로 사용되기도 하지만 일반적으로는 성장이 완료, 정지되고 그 이후에 일어나는 모든 과정을 가리킨다. 나이를 먹어감에 따라 생체의 여러 가지 기능이 저하되는데, 일반적으로 세포에 색소가 축적되거나 세포자체나 핵이 작아지는 현상이다. 개개의 세포 기능도 저하되고, 세포 내에 색소가 침착되며, 기관은 암갈색을 띤다. 또한 피부는 얇아지고 털주머니도 위축되며, 모발은 색소를 잃고 탈모된다. 현재 많은 학자들은 세포내 DNA가 끊어지거나 끊어진 경우 수복력이 감소하거나, 면역력이 저하하기 때문으로 보고 있다. 노화가 일어나는 것은 세포의 종류에 따라서 크게 다른데 신경세포처럼 태어나서 죽을 때까지 세포분열하지 않는 세포는 노화가 두드러지고 고환이나 골수의 세포처럼 항상 분열하는 세포는 노화현상이 거의 일어나지 않는다. 발병과 죽음의 확률이 높아지지만, 노쇠성 변화와 병적 변화와의 경제는 명확하지 않다. 노쇠를 야기하는 노화의 본질적 원인에 대해서는 아직 정설이 없다. |
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| AJKD | American Journal of Kidney Diseases |
|---|---|
| JOC | Journal of Oncologic Clinical(?) |
| AEM | Academic Emergency Medicine [journal]; analytical electron microscopy; ambulatory electrocardiograph... |
| AM | Academic Medicine [journal]; actomyosin; acute myelofibrosis; adult male; adult monocyte; aerospace ... |
| BMJ | bones, muscles, joints; British Medical Journal |
| JAMA | Journal of the American Medical Association |
|---|---|
| NEJM | New England Journal of Medicine |
| BLSA | Baltimore Longitudinal Study of Aging |
| CSHA | Canadian Study of Health and Aging |
| LSOA | Longitudinal Study of Aging |
| journal article | The predominant publication type for articles and other items indexed for nlm databases. (12 Dec 1998) |
|---|---|
| aging | The gradual changes in the structure and function of humans and animals that occur with the passage of time, that do not result from disease or other gross accidents, and that eventually lead to the increased probability of death as the person or animal grows older. It does not apply to microorganisms. (12 Dec 1998) |
| aging, premature | Changes in the organism associated with senescence, occurring at an accelerated rate. (12 Dec 1998) |
| cell aging | The decrease in the cell's ability to proliferate with the passing of time. Each cell is programmed for a certain number of cell divisions and at the end of that time proliferation halts. The cell enters a quiescent state after which it experiences cell death via the process of apoptosis. (12 Dec 1998) |
| clonal aging | The deterioration in successive generations of a clone; thus paramecia and other simple forms, if allowed to reproduce asexually for a number of generations, invariably undergo deterioration, the characters of each group of descendants progressively departing from those of the original sexually produced ancestor. (05 Mar 2000) |
| skin aging | The process of aging due to changes in the structure and elasticity of the skin over time. It may be a part of physiological aging or it may be due to the effects of ultraviolet radiation, usually through exposure to sunlight. (12 Dec 1998) |
| erythrocyte aging | Senescence of the red blood cell. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days. (12 Dec 1998) |
| retrospective studies | Studies used to test aetiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. (12 Dec 1998) |
| pharmalogical studies | <pharmacology> Studies to assess the potential harmful or other effects of drugs (16 Dec 1997) |
| clinical studies | <pharmacology> Human studies that are designed to measure the safety, efficacy, and appropriate dosage of a new drug or biological. Clinical studies routinely involve the use of a placebo group that is given an inactive substance that looks like the test product. (14 Nov 1997) |
| cohort studies | Studies in which subsets of a defined population are identified. These groups may or may not be exposed to factors hypothesised to influence the probability of the occurrence of a particular disease or other outcome. Cohorts are defined populations which, as a whole, are followed in an attempt to determine distinguishing subgroup characteristics. (12 Dec 1998) |
| combination studies | <pharmacology> Studies in which a new drug is evaluated in combination with existing drugs. (09 Jan 1998) |
| multicenter studies | Controlled studies which are planned and carried out by several cooperating institutions to assess certain variables and outcomes in specific patient populations, for example, a multicenter study of congenital anomalies in children. (12 Dec 1998) |
| multivariate studies | The use of statistical techniques for the simultaneous investigations of the influence of several variables. (05 Mar 2000) |
| preclinical studies | <pharmacology> Studies in which a drug is tested on animals and in other non-human test systems. Safety information from such studies are used to support an investigational new drug application. (14 Nov 1997) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|