| animals, domestic | Animals which have become adapted through breeding in captivity to a life intimately associated with man. They include animals domesticated by man to live and breed in a tame condition on farms or ranches (e.g., horses, cattle, sheep) and those raised or kept for pleasure and companionship (e.g., dogs, cats, horses). (12 Dec 1998) |
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| animals, inbred strains | Animals produced by the mating of littermates or siblings over multiple generations. The resultant strain of animals is virtually identical genotypically. Highly inbred animal lines allow the study of certain traits in a relatively pure form. (12 Dec 1998) |
| animals, suckling | Young, unweaned mammals. Refers to nursing animals whether nourished by their biological mother, foster mother, or bottle fed. (12 Dec 1998) |
| animals, transgenic | Animals, or the offspring of such animals, into which cloned genetic material has been experimentally transferred by microinjection of foreign DNA, either directly or into embryos or differentiated cell types. Transgenic rabbits, mice, fish, xenopus, sheep, pigs, and chickens have been produced using genes of sea urchins, candida, drosophila, and mice. (12 Dec 1998) |
| animals, wild | Animals considered to be wild or feral or not adapted for domestic use. It does not include wild animals in zoos for which animals, zoo is available. (12 Dec 1998) |
| radiation injuries, experimental | Harmful effects of exposure to ionizing or non-ionizing radiation produced experimentally in chordates. (12 Dec 1998) |
| games, experimental | Games designed to provide information on hypotheses, policies, procedure or strategies. (12 Dec 1998) |
| psychology, experimental | The branch of psychology which seeks to learn more about the fundamental causes of behaviour by studying various psychologic phenomena in controlled experimental situations. (12 Dec 1998) |
| neuritis, experimental allergic | An autoimmune demyelinating disorder of peripheral nerves produced by injection of peripheral nerve tissue protein. (12 Dec 1998) |
| diabetes mellitus, experimental | Diabetes mellitus induced experimentally by administration of various diabetogenic agents or by pancreatectomy. (12 Dec 1998) |
| implants, experimental | Artificial substitutes for body parts and materials inserted into organisms during experimental studies. (12 Dec 1998) |
| experimental | 1. Of, relating to or based on experience: empirical. 2. Of a disease: intentionally produced especially in laboratory animals for the purpose of study. (18 Nov 1997) |
| experimental allergic encephalitis | <pathology> An autoimmune disease that can be induced in various experimental animals by the injection of homogenised brain or spinal cord in Freund's adjuvant. The antigen appears to be a basic protein present in myelin and the response is characterised by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as a model for demyelinating diseases, although whether this is entirely justifiable is not clear. (18 Nov 1997) |
| experimental allergic encephalomyelitis | <pathology> An autoimmune disease that can be induced in various experimental animals by the injection of homogenised brain or spinal cord in Freund's adjuvant. The antigen appears to be a basic protein present in myelin and the response is characterised by focal areas of lymphocyte and macrophage infiltration into the brain, associated with demyelination and destruction of the blood-brain barrier. Sometimes used as a model for demyelinating diseases, although whether this is entirely justifiable is not clear. (18 Nov 1997) |
| experimental error | The total error of measurement ascribed to the conduct of an empirical observation. It is commonly expressed as the standard deviation of replicated experiments. There may be many components, including those in the sampling procedure, the measurements, injudicious choice of a model, observer bias, etc. (05 Mar 2000) |