| 영문 | protein | 한글 | 단백질 |
|---|---|---|---|
| 설명 | 탄소, 수소, 산소, 질소, 황을 함유하고 있는 유기화합물로, 모든 세포의 원형질을 이루고 있는 기본 구성물질이다. 단백질은 그 단위인 아미노산들이 펩티드결합에 의해 결합되어 있으며, 보통 20개의 아미노산들이 다른 순서와 조성을 가지고 배열되어, 독특한 하나의 단백질을 형성하게 된다. |
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| 영문 | receptor | 한글 | 수용체 |
|---|---|---|---|
| 설명 | 세포질내 또는 세포표면에 존재하는 분자구조로서 특이물질과 선택적으로 결합하며 결합에 의해 특이한 생리적 작용을 나타낸다. 펩티드호르몬, 신경전달물질, 항원, 보체, 면역글로불린에 대한 세포표면 수용체와 스테로이드에 대한 세포질내 수용체가 있다. |
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| 영문 | interleukin | 한글 | 인터루킨 |
|---|---|---|---|
| 설명 | 면역계가 질병과 감염에 맞서 싸우도록 자극하는 단백질의 한 형태. 약칭은 IL이다. 백혈구(림프구)에서 만들어진다. 백혈구는 몸 안에 들어온 세균이나 다른 해로운 물질을 파괴하거나 제거한다. 여러 종류의 백혈구에서 인터루킨이 발견되었은데 물리적-화학적 성상이 확인된 것으로는 IL1, IL2, IL3, IL4, IL5, IL6 등이 있다. 이 인터루킨들은 함께 작용하여 백혈구가 질병에 대항하도록 연쇄적으로 반응한다. 예를 들어 상처 부위에 세균이 침입하면 큰포식세포라는 백혈구가 세균을 인식하고 인터루킨을 방출한다. 인터루킨은 백혈구의 일종인 T세포를 활성화한다. T세포는 세균을 파괴하며 인터루킨과 다른 유사한 화학물질을 방출하여 면역계의 여러 세포를 활성화시켜서 세균을 공격하게 한다. 당초에 인터루킨이라는 명칭은 백혈구간의 정보전달을 수행하는 물질이라는 의미로 붙여졌으나 현재 알려져 있는 10여종은 생산세포나 반응세포, 기능 등의 점에서 연관된다고는 할 수 없다. 인터루킨의 발견으로 몇 가지 형태의 암과 그 밖의 여러 질병의 치료가 보다 쉬워졌다. |
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| antag | antagonist |
|---|---|
| CA | anterior commissure [Lat. commissura anterior]; calcium antagonist; California [rabbit]; cancer; Can... |
| FAA | folic acid antagonist; formaldehyde, acetic acid, alcohol |
| ILR | interleukin receptor; irreversible loss rate |
| ILRA | interleukin receptor alpha |
| IRAP | Interleukin Receptor Antagonist Protein |
|---|---|
| IL 1Ra | interleukin 1 receptor antagonist protein |
| IL-1ra | Interleukin 1 receptor antagonist |
| rhIL-1ra | Recombinant human interleukin-1 receptor antagonist |
| IRAP | IL 1 receptor antagonist protein |
| cAMP receptor protein | catabolite (gene) activator protein |
|---|---|
| receptor protein | An intracellular protein (or protein fraction) that has a high specific affinity for binding a known stimulus to cellular activity, such as a steroid hormone or adenosine 3',5'-cyclic phosphate. (05 Mar 2000) |
| receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of receptors. Many growth and differentiation factor receptors contain this domain. It is critical for the signal transduction pathways required for mitogenesis, transformation, and cell differentiation. Registry number: EC 2.7.1.- (12 Dec 1998) |
| Cek4 receptor protein-tyrosine kinase | <enzyme> Isolated from mouse and chicken. Registry number: EC 2.7.1.- Synonym: cek4 protein, cek4 eph receptor, eph receptor cek4 (26 Jun 1999) |
| G-protein coupled receptor | <cell biology> Cell surface receptors that are coupled to G-proteins (GTP-binding protein). G-protein coupled receptors are thought to have seven membrane spanning domains and have been divided into 2 subclasses: those in which the binding site is in the extracellular domain for example receptors for glycoprotein hormones, such as thyroid stimulating hormone (TSH) and follicle-stimulating hormone (FSH) and those in which the ligand binding site is likely to be in the plane of the 7 transmembrane domains for example rhodopsin and receptors for small neurotransmitters and hormones for example muscarinic acetylcholine receptor. (18 Nov 1997) |
| cyclic AMP receptor protein | A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (cyclic AMP receptors), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of cyclic AMP-dependent protein kinases. (12 Dec 1998) |
| insulin receptor protein-tyrosine kinase | <enzyme> A catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of the insulin receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| insulin receptor substrate-1 protein | <chemical> Amino acid sequence given in first source; a 180 kD protein that contains multiple phosphorylated tyrosine residues after insulin stimulation; human and rat forms (hirs-1 and irs-1) are homologous Synonym: insulin receptor substrate-1-like protein, irs-1 protein, irs-1 gene product, hirs-1 protein, hirs-1 gene product, insulin receptor substrate 1, insulin receptor substrate-1 (05 Dec 1998) |
| TGF-beta receptor protein kinase | <enzyme> Belongs to the receptor-type serine-threonine kinase subfamily; from chick embryo, related to type II receptor for tgf-beta; 502 aa residues, mw 56,766 da; aa sequence given in first source Registry number: EC 2.7.1.- Synonym: tgf-beta rpk, rpk-1, rpk-2 (26 Jun 1999) |
| epidermal growth factor receptor protein-tyrosine kinase | <enzyme> The catalytic protein-tyrosine kinase domain found on the cytoplasmic beta-portion of epidermal growth factor receptor. Registry number: EC 2.7.1.- (12 Dec 1998) |
| light-repressible receptor protein kinase | <enzyme> Photo-regulated protein isolated from arabidopsis thaliana; genbank x97774 Registry number: EC 2.7.1.- Synonym: lrrpk gene product (26 Jun 1999) |
| aldosterone antagonist | An agent that opposes the action of the adrenal hormone aldosterone on renal tubular mineralocorticoid retention; these agents, e.g., spironolactone, are useful in treating the hypertension of primary hyperaldosteronism, or the sodium retention of secondary hyperaldosteronism. (05 Mar 2000) |
| antagonist | <pharmacology> A substance that tends to nullify the action of another, as a drug that binds to a cell receptor without eliciting a biological response. Origin: Gr. Antagonistes = an opponent (18 Nov 1997) |
| associated antagonist | One of two muscles or groups of muscles which pull in nearly opposite directions, but which, when acting together, move the part in a path between their diverging lines of action. (05 Mar 2000) |
| beta-adrenoreceptor antagonist | A class of drugs that compete with beta-adrenergic agonists for available receptor sites; some compete for both b1 and b2 receptors (e.g., propranolol) while others are primarily either b1 (e.g., metoprolol) or b2 blockers; used in the treatment of a variety of cardiovascular diseases where beta-adrenergic blockade is desirable. Synonym: beta-adrenergic receptor blocking agent, beta-adrenoreceptor antagonist, beta-blocker. (05 Mar 2000) |
Synonyms : Amgen Brand of Anakinra, Anakinra, Antril, IL-1 Inhibitor, Urine, IL-1Ra, IL1 Febrile Inhibitor, Interleukin 1 Inhibitor, Urine, Kineret, Synergen Brand of Anakinra, Urine-Derived IL1 Inhibitor, Anakinra Amgen Brand, Anakinra Synergen Brand, Febrile Inhibitor, IL1
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|