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dominantly inherited Levi's disease Dwarfism characterised by low birth weight, snub nose, and stocky build; autosomal dominant inheritance. There is a similar autosomal recessive phenotype.
Synonym: dominantly inherited Levi's disease.
(05 Mar 2000)
inherited Derived from a preformed genetic code present in the parents. Contrast with acquired.
(05 Mar 2000)
inherited albumin variants Types of human serum albumin, distinguished by characteristic mobility patterns on electrophoresis; each type is due to a mutation of a gene controlling albumin synthesis; the mutant genes are codominant with the normal gene for albumin A, and the group forms a system of genetic polymorphism; types include: albumin b (slow), found occasionally in persons of European ancestry; albumin Ghent (fast), found first at Ghent, Belgium; albumin Mexico (slow), found in Indians of Mexico and the southwestern United States; albumin Naskapi (fast), found in the Naskapi and other Indians of northern North America; and albumin Reading (fast), found first at Reading, England.
(05 Mar 2000)
inherited character A single attribute of an animal or plant that is transmitted at one locus from generation to generation in accordance with Mendel's law.
See: gene.
Synonym: unit character.
(05 Mar 2000)
acquired immunodeficiency disease Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV).
(12 Dec 1998)
Acquired Immunodeficiency Syndrome <immunology, syndrome> An epidemic disease caused by an infection by human immunodeficiency virus (HIV-1, HIV-2), a retrovirus that causes immune system failure and debilitation and is often accompanied by infections such as tuberculosis. AIDS is spread through direct contact with bodily fluids.
Acronym: AIDS
(10 May 1997)
bovine immunodeficiency virus A lentivirus causing lymphocytosis in cattle.
(05 Mar 2000)
malignancy and immunodeficiency <radiology> High risk of malignancy (especially lymphoma/leukaemia, GI tumours): X-linked agammaglobulinaemia (Bruton's), common variable immunodeficiency, severe combined immunodeficiency (SCID kids), ataxia-telangectasia, Wiscott-Aldrich syndrome, selective IgA deficiency
(12 Dec 1998)
cellular immunodeficiency with abnormal immunoglobulin synthesis An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal.
Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia.
(05 Mar 2000)
phagocytic dysfunction disorders immunodeficiency Suppression in number or function of phagocytic cells such as in chronic granulomatous disease.
Synonym: phagocytic dysfunction disorders immunodeficiency.
Origin: L. Phagedaena, Gr Phago, To eat.
(05 Mar 2000)
phagocytic dysfunction immunodeficiency Suppression in number or function of phagocytic cells such as in chronic granulomatous disease.
Synonym: phagocytic dysfunction disorders immunodeficiency.
Origin: L. Phagedaena, Gr Phago, To eat.
(05 Mar 2000)
combined immunodeficiency <immunology> Congenital immunodeficiency with thymic agenesis, lymphocyte depletion and hypogammaglobulinaemia: both cellular and humoral immune systems are affected and life expectancy is low unless marrow transplantation is successful.
(18 Nov 1997)
combined immunodeficiency syndrome <syndrome> A serious primary immunodeficiency affecting both T and B-cells.
(05 Mar 2000)
common variable immunodeficiency Heterogeneous group of immunodeficiency syndromes characterised by hypogammaglobulinaemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections.
(12 Dec 1998)
congenital severe combined immunodeficiency Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes.
(18 Nov 1997)
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