| protamine | Highly basic (arginine rich) protein that replaces histone in sperm heads, enabling DNA to pack in an extremely compacted form, for example clupein, iridin (4K). See: transition proteins. (18 Nov 1997) |
|---|---|
| protamine kinase | <enzyme> An aspect of protein kinase (ec 2.7.1.37) in which serine residues in protamines and histones are phosphorylated in the presence of ATP. Chemical name: ATP:protamine O-phosphotransferase Registry number: EC 2.7.1.70 (12 Dec 1998) |
| protamine sulfate | A purified mixture of simple protein principles from the sperm or testes of suitable species of fish; it is a heparin antagonist used in certain haemorrhagic states associated with increased amounts of heparin-like substances in the circulation and for the treatment of heparin overdosage. (05 Mar 2000) |
| protamine zinc insulin | Insulin modified by the addition of protamine and zinc chloride; it contains 40 or 80 units per ml. (05 Mar 2000) |
| insulin, protamine zinc | <chemical> A long-acting insulin with an approximate time of onset of 7 hours and duration of action 36 hours, consisting of bovine or pork insulin reacted with zinc chloride and protamine to form a protein complex from which insulin is slowly released. Pharmacological action: hypoglycaemic agents. Chemical name: Insulin protamine zinc (12 Dec 1998) |