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  • Ivermectin - »õâ A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
    Synonyms : Eqvalan, Ivomec, MK-933, Mectizan, Merck Brand of Ivermectin, Stromectol, Ivermectin Merck Brand, MK 933, MK933
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