| inositol | A cyclic hexahydric alcohol with 6 possible isomers. The biologically active form is myo inositol. (18 Nov 1997) |
|---|---|
| inositol 1,2,3,4,6-pentakisphosphate-2-phoshomonoesterase | <enzyme> Metabolises ins(1,2,3,4,6)p5 to ins(1,3,4,6)p4 Registry number: EC 3.1.3.- Synonym: 1,2,3,4,5-insp5-2-p monoesterase (26 Jun 1999) |
| inositol 1,2,3,5,6-pentakisphosphate 5-phosphatase | <enzyme> From foetal calf thymus; inhibited by thiol modifiers Registry number: EC 3.1.3.- Synonym: 1,2,3,5,6-insp5-5-phosphatase, ins(1,2,3,5,6)p5 5-phosphatase, insp5 5-phosphatase (26 Jun 1999) |
| inositol 1,3,4,5,6-pentakisphosphate-1-3-phosphatase | <enzyme> Removes a phosphate group at the 1 or 3 position or at both positions of ins(1,3,4,5,6)p5 Registry number: EC 3.1.3.- Synonym: 1,3,4,5,6-insp5-1-3-phosphatase (26 Jun 1999) |
| inositol 1,3,4,5-tetrakisphosphate 3-phosphatase | <enzyme> From rat liver; forms inositol-1,4,5-triphosphate Registry number: EC 3.1.3.62 Synonym: inositol 1,3,4,5-tetrakisphosphate 3-phosphomonoesterase, ins(1,3,4,5)p4 3-phosphatase, multiple inositol polyphosphate phosphatase, mipp enzyme (26 Jun 1999) |
| inositol 1,3,4,5-tetrakisphosphate phosphomonoesterase | <enzyme> Rat liver enzyme forms inositol 1,3,4-triphosphate Registry number: EC 3.1.3.- Synonym: inositol tetrakisphosphate phosphomonoesterase, ins(1,3,4,5)p4 phosphomonoesterase, ins(1,3,4,5)p4 5-phosphatase, 1,4,5-triphosphate-1,2,4,5-tetrakisphosphate 5-phosphatase, inositol 1,3,4,5-polyphosphate 5-phosphatase (26 Jun 1999) |
| inositol 1,3,4-trisphosphate 4-phosphatase | <enzyme> Calf brain enzyme removes 4-phosphate from inositol 1,3,4-triphosphate; does not require magnesium; not inhibited by lithium Registry number: EC 3.1.3.- Synonym: inositol 1,3,4-triphosphate 4-phosphatase, intp 4-phosphatase (26 Jun 1999) |
| inositol 1,3,4-trisphosphate 5-6 kinase | <enzyme> Consider also EC 2.7.1.133 or EC 2.7.1.139 Registry number: EC 2.7.1.- Synonym: ins(1,3,4)p3 5-6 kinase (26 Jun 1999) |
| inositol 1,4,5-trisphosphate | <chemical> Intracellular messenger formed by the action of phospholipase c on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of b kinase or calmodulin. Chemical name: D-myo-Inositol, 1,4,5-tris(dihydrogen phosphate) (12 Dec 1998) |
| inositol 1-alpha-galactosyltransferase | <enzyme> Catalyses conversion of udpgalactose plus myo-inositol to galactinol plus udp Registry number: EC 2.4.1.123 Synonym: galactinol synthase (26 Jun 1999) |
| inositol 3 kinase | <enzyme> See phosphatidyl inositol 3 kinase. (18 Nov 1997) |
| inositol cyclic 1,2-phosphate 1-phosphodiesterase | <enzyme> Converts inositol 1:2-cyclic phosphate to inositol 2-phosphate; do not confuse with inositol 1,2 cyclic-phosphate 2-phosphohydrolase see annexin III Registry number: EC 3.1.4.- Synonym: cins(1,2)p hydrolase II (26 Jun 1999) |
| inositol hexakisphosphate kinase | <enzyme> 54-kD enzyme that catalyses formation of diphosphoinositol pentakisphosphate (pp-ip5) from inositol hexakisphosphate; the reverse reaction acts as an ATP synthase Registry number: EC 2.7.4.- Synonym: ip(6) kinase (26 Jun 1999) |
| inositol lipid | A membrane-anchored phospholipid that transduces hormonal signals by stimulating the release of any of several chemical messengers. (09 Oct 1997) |
| inositol NAD epimerase | <enzyme> Converts myo-inositol to scyllo-inositol and neoinositol; inosose also formed and reverse reaction Registry number: EC 1.1.1.- (26 Jun 1999) |
| glycosyl phosphatidyl inositol | gPI anchor |
|---|---|
| meso-inositol | 1. Generic term for any isomer of meso-inositol in which the hydroxyl groups are so arranged that the molecule as a whole possesses a plane of symmetry and is optically inactive. 2. Former name for myo-inositol. (05 Mar 2000) |
| myo-inositol | 1,2,3,5/4,6-Inositol;a constituent of various phosphatidylinositols and the most widely distributed form of inositol found in microorganisms, higher plants, and animals. In plants, it is found as phytic acid and as phytin; partially phosphorylated and free forms occur throughout nature, and in many tissues. (05 Mar 2000) |
| myo-inositol 1,4,5-triphosphate phosphatase | <enzyme> Neutral pH optimum; magnesium dependent Registry number: EC 3.1.- Synonym: i-p3ase, inositol 1,4,5-triphosphate phosphatase (26 Jun 1999) |
| myo-inositol-1 (or 4)-monophosphatase | <enzyme> Acts on inositol 1-phosphate, inositol 3-phosphate or inositol 4-phosphate; suhb gene product from e. Coli has been sequenced; do not confuse with impa protein Registry number: EC 3.1.3.25 Synonym: 1l-myo-inositol-1-phosphate phosphohydrolase, inositol-1-phosphate phosphohydrolase, myo-inositol-1-phosphatase, inositol phosphatase, myo-inositol monophosphatase, 1l-myo-inositol-1-phosphatase, inositol monophosphatase, suhb gene product, inositol monophosphate phosphatase impa (26 Jun 1999) |
| myo-inositol-1-phosphate dehydrogenase | <enzyme> Requires nad+, forms ribulose 5-phosphate Registry number: EC 1.1.1.- Synonym: inositol-1-phosphate dehydrogenase (26 Jun 1999) |
| myo-inositol-1-phosphate synthase | <enzyme> An enzyme that catalyses the formation of myo-inositol-1-phosphate from glucose-6-phosphate in the presence of NAD. Chemical name: 1L-myo-Inositol-1-phosphate lyase (isomerizing) Registry number: EC 5.5.1.4 (12 Dec 1998) |
| myo-inositol-4-phosphatase | <enzyme> Brain and liver enzymes are li-sensitive Registry number: EC 3.1.3.- (26 Jun 1999) |
| myo-inositol-trisphosphate 3-kinase | <enzyme> Converts inositol triphosphate to 1,3,4,5-tetrakisphosphate Registry number: EC 2.7.1.127 Synonym: inositol 1,4,5-triphosphate kinase, 1,4,5-intp kinase, inositol(1,4,5)p3 3-kinase, myo-inositol 1,4,5-triphosphate-3-kinase, inositol 1,4,5-trisphosphate kinase (26 Jun 1999) |
| myo-inositol-trisphosphate 6-kinase | <enzyme> Forms inositol 1,3,4,6-tetrakisphosphate and inositol 1,3,4,5-tetrakisphosphate in a ratio of 5:1 Registry number: EC 2.7.1.133 Synonym: inositol 1,3,4-p3 kinase, ins 1,3,4-p3 kinase, myo-inositol 1,3,4-tris phosphate 6-kinase, inositol-1,3,4-trisphosphate 5,6-kinase, inositol-trisphosphate 6-kinase (26 Jun 1999) |
| cyclic inositol phosphate | 1, 2 cyclic derivatives of inositol phosphatide that are invariably formed during enzymic hydrolysis of phosphatidyl inositol species. Have been proposed as second messengers in hormone activated pathways. (18 Nov 1997) |
| SH2-containing inositol phosphatase | <enzyme> 145-kD protein with both phosphatidylinositol 3,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate polyphosphate 5-phosphatase activity; associates with shc in response to multiple cytokines; genbank u39203 and y14385 Registry number: EC 3.1.3.- Synonym: ship protein, inpp5d gene product, sh2- and sh3-containing inositol polyphosphate-5-phosphatase, pp135 ship, ship2 protein (26 Jun 1999) |
| D-myo-inositol-3-phosphate synthase | <enzyme> Catalyses conversion of d-glucose-6-phosphate to d-myo-inositol-3-phosphate Registry number: EC 5.5.1.- Synonym: inositol-3-phosphate synthase, ins3p synthase (26 Jun 1999) |