| IL-1 |
Interleukin-1 (IL-1) is secreted by the macrophages, monocytes and dendritic cells. It is an important part of the inflammatory response. It increases the expression of adhesion factors on endothelial cells to enable transmigration of leukocytes. It also re-sets the hypothalamus thermoregulatory center, leading to an increased body temperature which expresses itself as fever. It is therefore called an endogenous pyrogen. ...
출처: en.wikipedia.org/wiki/IL-1
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| IL-1 |
interleukin-1. A type of biological response modifier that stimulates immune system cells that fight disease, and is involved in inflammatory responses. There are two forms of IL-1, IL-1 alfa and IL-1 beta. Both forms of IL-1 are produced by the body, and can also be made in the laboratory.
출처: www.stjude.org/glossary
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| IL-1 |
Produced by activated macrophages, endothelial cells, and B cells, IL-1 is a cytokine that induces inflammatory responses. As a proinflammatory cytokine, IL-1 has a role in immune, degradative, and growth-promoting processes. Belonging to this class of cytokines, IL-1?and IL-1a are agonists while IL-1Ra is an antagonist of the IL-1 receptor.
출처: www.jco.org/cgi/glossarylookup
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| IL-1 |
one of the pro-inflammatory cytokines in the immune system thought to play a role in the disease process of RA, including bone erosion; the IL-1 receptor is the target of a new BRM, anakinra.
출처: www.raacademy.com/glossary/Glossary.jsp
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