| IDU | <drug> Analogue of thymidine that inhibits the replication of DNA viruses. Used in the treatment of Herpes simplex and varicella zoster. (18 Nov 1997) |
|---|---|
| iduronate | The salt or ester of iduronic acid. (05 Mar 2000) |
| iduronate sulfatase | <enzyme> An enzyme that specifically cleaves the ester sulfate of iduronic acid, and is required for the desulfation of 2-sulfate iduronate residues in heparan sulfate. It is also required in dermatan sulfate degradation. Its deficiency has been demonstrated in Hunter's syndrome, which is characterised by an excess of dermatan sulfate and heparan sulfate. Chemical name: L-Iduronate-2-sulfate 2-sulfohydrolase Registry number: EC 3.1.6.13 (20 Sep 2002) |
| iduronic acid | <chemical> Component of dermatan sulfate. Differs in configuration from glucuronic acid only at the c-5 position. Chemical name: Iduronic acid (12 Dec 1998) |
| iduronidase | <enzyme> An enzyme that hydrolyzes iduronosidic linkages in desulfated dermatan. Deficiency of this enzyme produces hurler's syndrome. Chemical name: Glycosaminoglycan alpha-L-iduronohydrolase Registry number: EC 3.2.1.76 (12 Dec 1998) |