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hyperosmolar nonketotic coma A complication seen in diabetes mellitus in which very marked hyperglycaemia occurs (such as levels over 800 mg/dL) causing osmotic shifts in water in brain cells and resulting in coma. It can be fatal or lead to permanent neurologic damage. Ketoacidosis does not occur in these cases.
Synonym: nonketotic hyperglycaemia.
(05 Mar 2000)
hyperosmolarity An increase in the osmotic concentration of a solution expressed as osmoles of solute per liter of solution.
(05 Mar 2000)
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hyperglycaemic hyperosmolar nonketotic coma A syndrome consisting of extreme hyperglycaemia, serum hyperosmolarity and dehydration in the absence of ketosis and acidosis.
(12 Dec 1998)
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