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human plasma protein fraction A sterile solution of selected proteins derived from the blood plasma of adult human donors, containing 4.5 to 5.5 g of protein per 100 ml, of which 83 to 90% is albumin and the remainder is alpha-and beta-globulins; used as a blood volume supporter.
(05 Mar 2000)
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dried human plasma protein fraction Freeze-dried human plasma protein fraction.
(05 Mar 2000)
human antihemophilic fraction A lyophilised concentrate of factor VIII, obtained from fresh normal human plasma; used as a haemostatic agent in haemophilia.
Synonym: antihemophilic globulin, human antihemophilic fraction.
(05 Mar 2000)
fraction I protein <protein> See ribulose bisphosphate carboxylase/oxidase RUBISCO).
(18 Nov 1997)
normal human plasma Sterile plasma obtained by pooling approximately equal amounts of the liquid portion of citrated whole blood from eight or more adult humans who have been certified as free from any disease which is tranmissible by transfusion, and treating it with ultraviolet irradiation to destroy possible bacterial and viral contaminants.
(05 Mar 2000)
plasma protein <haematology> One of the hundreds of different proteins present in blood plasma, including carrier proteins (such albumin, transferrin and haptoglobin), fibrinogen and other coagulation factors, complement components, immunoglobulins, enzyme inhibitors, precursors of substances such as angiotension and bradykinin and many other types of proteins.
(14 Oct 1997)
pregnancy-associated alpha-plasma protein An alpha 2-macroglobulin, molecular weight approximately 750,000 now believed to be a pregnancy-specific protein. Its plasma levels increase steadily during the second trimester and continue to rise until the end of gestation.
(12 Dec 1998)
pregnancy-associated beta-plasma protein A beta-globulin now believed to be a pregnancy-specific protein. Its plasma levels increase steadily during pregnancy until the end of gestation.
(12 Dec 1998)
aetiological fraction <epidemiology> The reduction in disease when a risk factor is removed. If I* is the number of people that a risk factor is responsible for and I is the total number of cases over the same period, then the aetiological fraction is I*/I. Equivalently, the aetiological fraction is (I-Io)/I. Where Io is the number of cases in the absence of the risk factor. Also known as the attributable fraction.
(05 Dec 1998)
amorphous fraction of adrenal cortex Noncrystalline residue of an acetone extract of the adrenal cortex after crystalline steroids, e.g., corticosterone, deoxycorticosterone, etc., have been isolated.
(05 Mar 2000)
attributable fraction <epidemiology> The same as aetiological fraction.
(05 Dec 1998)
recombination fraction The proportion of progeny of a mating pair of specific genotype and coupling phase that are recombinant; there must be no differential selection among the possible types of progeny, and the recombination fraction should be the same regardless of the alleles involved or their coupling phase.
(05 Mar 2000)
regurgitant fraction The amount of blood regurgitated into a cardiac chamber divided by the stroke output; normally, no blood regurgitates; in patients with severe valvular lesions such as mitral or aortic insufficiency, regurgitation can approach 80%; this fraction affords a quantitative measure of the severity of the valvular lesion.
(05 Mar 2000)
microsomal fraction Artifactual vesicles formed from the endoplasmic reticulum when cells are disrupted. They are isolated by differential centrifugation and are composed of three structural features: rough vesicles, smooth vesicles, and ribosomes. Numerous enzyme activities are associated with the microsomal fraction. (glick, glossary of biochemistry and molecular biology, 1990; from rieger et al., glossary of genetics: classical and molecular, 5th ed)
(12 Dec 1998)
mole fraction The ratio of the moles of one component of a system to the total moles of all the components present.
(05 Mar 2000)
ejection fraction <cardiology> A measure of ventricular contractility, equal to normally 65
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