| Hodgkin's d. |
a form of malignant lymphoma characterized by painless, progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue; other symptoms may include anorexia, lassitude, weight loss, fever, pruritus, night sweats, and anemia. The characteristic histologic feature is presence of Reed-Sternberg cells. It affects twice as many males as females and is usually considered to be neoplastic in origin, although neither an infectious origin nor an immune response to Reed-Sternberg cells has been excluded. Four types have been distinguished according to histopathologic criteria, three with diffuse patterns (lymphocyte predominance type, mixed cellularity type, and lymphocyte depletion type) and one with a nodular pattern (nodular sclerosis type). Called also Reed-Hodgkin d. and Hodgkin's lymphoma. See also non-Hodgkin's lymphoma, under lymphoma.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| Hodgkin's d., lymphocyte depletion type |
a type of Hodgkin's disease characterized by a low number of lymphocytes and an abundance of Reed-Sternberg cells with fibrosis; it is the most aggressive of the three diffuse types of Hodgkin's disease. Called also Hodgkin's sarcoma.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| Hodgkin's d., lymphocyte predominance type |
a type of Hodgkin's disease characterized by a diffuse to slightly nodular infiltrate with abundant mature lymphocytes and varying numbers of benign histiocytes; there are few Reed-Sternberg cells and the degree of malignancy is low. Most patients are males under age 35. Called also paragranuloma.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| Hodgkin's d., mixed cellularity type |
a type of Hodgkin's disease intermediate between the lymphocyte predominance and lymphocyte depletion types; Reed-Sternberg cells are plentiful and there are more inflammatory cells, such as eosinophils and plasma cells, than in the lymphocyte predominance type.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| Hodgkin's d., nodular sclerosis type |
a type of Hodgkin's disease in which Reed-Sternberg cells are in the form of lacunar cells and bands of collagen divide the lymphoid tissue into nodules; there are varying numbers of lymphocytes and inflammatory cells such as eosinophils and plasma cells. This type is most common in young women and often has a low grade of malignancy.
출처: www.mercksource.com/pp/us/cns/cns_health_library.j...
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