| Hirschsprung's disease | <disease> A congenital condition which results in an enlarged and poorly functioning colon due to abnormal intestinal motility. These patients are at risk for intestinal obstruction. Constipation, vomiting, abdominal distention, poor weight gain, a retarded growth are common. Treatment include the use of a temporary colostomy with later resection of the affected portion of bowel. Symptoms are eliminated in up to 90% of patients after surgery. Outcomes are better with early intervention. <radiology> Aganglionosis of myenteric plexus of colon, functional obstruction, aganglionic segment of normal caliber, continuous involvement, from rectum proximally, males (80%), usually presents by 6 weeks, complications: enterocolitis, perforation, associated with Down syndrome Differential diagnosis: ileal atresia, meconium ileus (no air-fluid levels) (27 Sep 1997) |
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| disease, Hirschsprung's | Absence of nerves (ganglia) in the bowel wall starting in the anus extending up a variable distance with enlargement of the bowel above that point. Hirschsprung's disease is the commonest cause of lower intestinal obstruction in the newborn and, later, one of the causes of chronic constipation. Also called congenital aganglionic megacolon. (12 Dec 1998) |
| Hirschsprung, Harald | <person> Danish physician, 1830-1916. See: Hirschsprung's disease. (05 Mar 2000) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| acute disease | Disease having a short and relatively severe course. (12 Dec 1998) |
| Adams-Stokes disease | <syndrome> Transient asystole or ventricular fibrillation in the presence of atrioventricular block. (12 Dec 1998) |
| Addison-Biermer disease | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| Addison's disease | <endocrinology> A rare endocrine disease that results from the underproduction of aldosterone and cortisol (hormones) by the adrenal glands. Symptoms include weakness, low blood pressure, anaemia, low blood sugar and electrolyte abnormalities. (27 Sep 1997) |
| adult-onset still's disease | Although Still's disease was first described in children, it is known to begin in adults. See: Still's disease. (12 Dec 1998) |
| Akabane disease | A disease of cattle, sheep and goats, caused by the Akabane virus and characterised by foetal or neonatal arthrogryposis and hydranencephaly, abortions, and foetal death; the causative virus is transmitted by mosquitoes in Japan and by the midge Culicoides brevitarsis in Australia. (05 Mar 2000) |
| akamushi disease | See Typhus, scrub. (12 Dec 1998) |