| herpes simplex | <virology> The Herpes simplex virus is responsible for several different infections in humans: gingivostomatitis (in children), pharyngitis, oral and lip lesions (recurrent Herpes simplex type 1), proctitis, (type 2) and genital herpes (type 2). (27 Sep 1997) |
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| herpes simplex encephalitis | The most common acute encephalitis, caused by HSV-1; affects persons of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe haemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells. Synonym: acute inclusion body encephalitis, herpes encephalitis. (05 Mar 2000) |
| herpes simplex keratitis | <ophthalmology, pathology> A serious viral infection of the cornea that can result in a nonpenetrating erosion (corneal ulcer) of the cornea. The causative agent is Herpes zoster. Recurrences may be triggered by stress, exposure to sunlight, use of immunosuppressive medications or another illness. Treatment includes antiviral eyedrops. (27 Sep 1997) |
| herpes simplex type 1 | A virus that causes cold sores and fever blisters. (12 Dec 1998) |
| herpes simplex type 2 | Different from herpes simplex type 1, herpes simplex 2 causes genital herpes. (12 Dec 1998) |
| herpes simplex virus | <virology> A virus in the family Herpesviridae. Type 1 HSVcauses blisters on the lips, nostrils, and possibly on the lining of the eyelids. Type 2 HSV causes blisters and lesions on and aroundgenitalia. (09 Oct 1997) |
| herpes simplex virus 1 helicase-primase | <enzyme> Complex of three herpes-encoded gene products (ul52, ul5, and ul8) in addition to helicase activity, contains a tightly associated complex that may prime lagging strand synthesis as it unwinds DNA at the viral replication fork Registry number: EC 3.1.- Synonym: hsv-1 helicase-primase, ul5 protein, hsv helicase-primase complex, ul52 protein, ul8 protein (26 Jun 1999) |
| herpes simplex virus DNA polymerase | <enzyme> 3'-5'-exonuclease activity is associated with herpes simplex virus DNA polymerase; interacts with hsv-1 ul42 protein Registry number: EC 3.1.11.- Synonym: hsv DNA polymerase, polymerase associated exonuclease, herpes simplex virus 1 ul30 polymerase, hsv-1 ul30 protein, DNA polymerase ul30, hsv-1 (26 Jun 1999) |
| herpes simplex virus protein vmw65 | Trans-acting protein that combines with host factors to induce immediate early gene transcription in herpes simplex virus. (12 Dec 1998) |
| herpes simplex virus type 1 UL13 protein kinase | <enzyme> Phosphorylates icp22 and involved in the accumulation of alpha and gamma mrnas and proteins in the infected cells; aa sequence has been determined Registry number: EC 2.7.1.- Synonym: ul13 protein kinase, hsv-1, hsv-1 ul13 protein, hsv-1 ul13 pk, u(l)13 protein kinase, protein kinase ul13 (26 Jun 1999) |
| acne simplex | <dermatology> A form of acne which results from the bacterial infection of cysts deep within the skin. Generally requires treatment with antibiotics and other agents (Isotretinoin). Without treatment cystic acne may result in scarring. (27 Sep 1997) |
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| adiposis tuberosa simplex | A condition resembling adiposis dolorosa, in which the fat occurs in small, nodular masses, which are sensitive to touch and may be spontaneously painful, on the abdomen or on the extremities. (05 Mar 2000) |
| articulatio simplex | One composed of two bones only. Synonym: articulatio simplex. (05 Mar 2000) |
| carcinoma simplex | An obsolete term for any form of carcinoma in which the relative proportions of stroma and neoplastic epithelial cells are not unusual, i.e., stromal elements are not comparatively abundant, nor are they reduced in amount or lacking; an obsolete term for a carcinoma lacking any identifiable microscopic pattern, such as glandular structure. (05 Mar 2000) |
| verruca simplex | A keratotic papilloma of the epidermis which occurs most frequently in young persons as a result of localised infection by human papilloma virus, usually types 2 and 4; the lesions are of variable duration, eventually undergoing spontaneous regression, and are both exophytic and endophytic, with hyperkeratosis, parakeratosis, hypergranulosis, koilocytosis, and papillomatosis. Synonym: common wart, infectious warts, verruca simplex, viral wart. (05 Mar 2000) |
| periodontitis simplex | Horizontal resorption of the alveolar process with pockets of even depth on adjacent teeth; traumatic occlusion is not a factor. (05 Mar 2000) |
| pneumothorax simplex | Pneumothorax, without known cause, in an otherwise healthy person. (05 Mar 2000) |
| crus membranaceum simplex ductus saemicircularis | The non-ampullary end of the lateral saemicircular duct that opens independently into the utricle. Synonym: crus membranaceum simplex ductus saemicircularis, simple membranous limb of saemicircular duct. (05 Mar 2000) |
| scarlatina simplex | A mild form of the disease. (05 Mar 2000) |
| prurigo simplex | A mild form of prurigo having a pronounced tendency to relapse. (05 Mar 2000) |
| xanthoma tuberosum simplex | Xanthomatosis associated with familial type II, and occasionally type III, hyperlipoproteinaemia. Synonym: xanthoma tuberosum simplex. (05 Mar 2000) |
| purpura simplex | The eruption of petechiae or larger ecchymoses, usually unaccompanied by constitutional symptoms and not associated with systemic illness. Synonym: nonthrombocytopenic purpura. (05 Mar 2000) |
| dermatitis simplex | Blushing or redness of the skin caused by a toxic reaction or a neurovascular phenomenon. Synonym: dermatitis simplex. (05 Mar 2000) |
| ichthyosis simplex | most common form of ichthyosis characterised by prominent scaling especially on the exterior surfaces of the extremities. It is inherited as an autosomal dominant trait. (12 Dec 1998) |
| epidermolysis bullosa simplex | This represents a group of rare inherited disorders in which blistering of the skin occurs in response to skin trauma. Large fluid-filled blisters can occur in response to injury, skin rubbing, chafing or even increases in room temperature. Secondary bacterial infection of the blisters is common. Complications include oesophageal stricture, infections, loss of function of hands and feet and malnutrition. The dermatologist is the expert in the evaluation and treatment of this disorder. (27 Sep 1997) |