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hepatitis B core antigen <virology> (HBcAb, HBcAg), the antigen found in the core of the Dane particle (which is the complete virus) and also in hepatocyte nuclei in hepatitis B infections.
(05 Mar 2000)
hepatitis antigens Antigens from any of the hepatitis viruses including surface, core, and other associated antigens.
(12 Dec 1998)
hepatitis b e antigens A closely related group of antigens found in the plasma only during the infective phase of hepatitis b or in virulent chronic hepatitis b, probably indicating active virus replication; there are three subtypes which may exist in a complex with immunoglobulins g.
(12 Dec 1998)
hepatitis b surface antigens Those hepatitis b antigens found on the surface of the dane particle and on the 20 nm spherical and tubular particles. Several subspecificities of the surface antigen are known. These were formerly called the Australia antigen.
(12 Dec 1998)
hepatitis c antigens Antigens of the virions of hepatitis c-like viruses, their surface, core, or other associated antigens.
(12 Dec 1998)
atomic core The nucleus plus the nonvalence electrons.
(05 Mar 2000)
viral core proteins Proteins found mainly in icosahedral DNA and RNA viruses. They consist of proteins directly associated with the nucleic acid inside the nucleocapsid.
(12 Dec 1998)
central core disease A congenital myopathy characterised by hypotonia, delay of motor development in infancy, and nonprogressive or slowly progressive muscle weakness; on biopsy the central core of muscle fibres stains abnormally, myofibrils are abnormally compact, and there is virtual absence of mitochondria and sarcoplasmic reticulum; histochemically, the cores are devoid of oxidative enzyme, phosphorylase, and ATPase activity; autosomal dominant inheritance, often subclinical.
(05 Mar 2000)
central core disease of muscle <neurology> One of the conditions that produces floppy baby syndrome. It causes hypotonia (floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise.
Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type I muscle fibres). The disease is inherited as a dominant trait. The CCD gene is on chromosome 19 (and involves ryanodine receptor-1).
Inheritance: autosomal dominant.
(12 Dec 1998)
central transactional core The reticular activating system of the brain.
(05 Mar 2000)
muscle, central core disease of One of the conditions that produces 'floppy baby' syndrome. Ccd causes hypotonia (inadequately toned muscles characterised by floppiness) in the newborn baby, slowly progressive muscle weakness, and muscle cramps after exercise. Muscle biopsy shows a key diagnostic finding (absent mitochondria in the centre of many type i muscle fibres). Ccd is inherited as a dominant trait. The ccd gene is on chromosome 19 (and involves ryanodine receptor-1).
(12 Dec 1998)
core 1. The central mass of necrotic tissue in a boil.
2. A metal casting, usually with a post in the canal of a tooth root, designed to retain an artificial crown.
3. A sectional record, usually of plaster of Paris or one of its derivatives, of the relationships of parts, such as teeth, metallic restorations, or copings.
Origin: L. Cor, heart
4. The pupil (of the eye).
Origin: G. Kore, pupil
(05 Mar 2000)
core biopsy Removal (with a large needle) of a piece of a lump. The piece is sent to the lab to see if the lump is benign or malignant.
(09 Oct 1997)
core II protein, ubiquinol-cytochrome c reductase <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source
Synonym: core II protein, uccreductase
(26 Jun 1999)
core I protein, ubiquinol-cytochrome c reductase <chemical> Member of the mitochondrial-protein-processing family; protein found in subunits of ubiquinol-cytochrome c reductase; amino acid sequence given in first source
Synonym: core I protein, uccreductase
(26 Jun 1999)
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