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hof The hollow in the cytoplasm of a cell that lodges the nucleus.
Origin: Ger. Court
(05 Mar 2000)
Hofbauer cell A large cell in the connective tissue of the chorionic villi; it appears to be a type of phagocyte.
(05 Mar 2000)
Hofbauer, J Isfred <person> U.S. Gynecologist, 1878-1961.
See: Hofbauer cell.
(05 Mar 2000)
Hoffa's operation In congenital dislocation of the hip, hollowing out the acetabulum and reduction of the head of the femur after severing the muscles inserted into the upper portion of the bone.
(05 Mar 2000)
Hoffa, Albert <person> German surgeon, 1859-1908.
See: Hoffa's operation.
(05 Mar 2000)
Hoffman, August Wilhelm <person> German chemist, 1818-1892.
See: Frei-Hoffmann reaction, Hoffman's violet.
(05 Mar 2000)
Hoffmann's duct The excretory duct of the pancreas that extends through the gland from tail to head where it empties into the duodenum at the greater duodenal papilla.
Synonym: ductus pancreaticus, Hoffmann's duct, Wirsung's canal, Wirsung's duct.
(05 Mar 2000)
Hoffmann's muscular atrophy Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised.
Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy.
(05 Mar 2000)
Hoffmann's phenomenon Excessive irritability of the sensory nerves to electrical or mechanical stimuli in tetany.
(05 Mar 2000)
Hoffmann's reflex <clinical sign> In latent tetany mild mechanical stimulation of the trigeminal nerve causes severe pain, flexion of the terminal phalanx of the thumb and of the second and third phalanges of one or more of the fingers when the volar surface of the terminal phalanx of the fingers is flicked.
Synonym: digital reflex, Hoffmann's reflex, snapping reflex.
(05 Mar 2000)
Hoffmann's sign <clinical sign> In latent tetany mild mechanical stimulation of the trigeminal nerve causes severe pain, flexion of the terminal phalanx of the thumb and of the second and third phalanges of one or more of the fingers when the volar surface of the terminal phalanx of the fingers is flicked.
Synonym: digital reflex, Hoffmann's reflex, snapping reflex.
(05 Mar 2000)
Hoffmann, Freidrich <person> German physician, 1660-1742. Professor of Anatomy and Surgery at Halle, noted for clinical observations of a variety of infectious diseases.
(05 Mar 2000)
Hoffmann, Johann <person> German neurologist, 1857-1919.
See: Hoffmann's muscular atrophy, Hoffmann's phenomenon, Hoffmann's reflex, Hoffmann's sign, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy.
(05 Mar 2000)
Hoffmann, Moritz <person> German anatomist, 1622-1698.
See: Hoffmann's duct.
(05 Mar 2000)
Hofmann's bacillus <bacteria> A nonpathogenic species found in normal throats.
Synonym: Hofmann's bacillus.
(05 Mar 2000)
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