| plus | 1. <mathematics> More, required to be added; positive, as distinguished from negative; opposed to minus. 2. Hence, in a literary sense, additional; real; actual. "Success goes invariably with a certain plus or positive power." (Emerson) 3. <mathematics> Plus sign, the sign (+) which denotes addition, or a positive quantity. Origin: L, more; akin to Gr, and cf. Piu, Pleonasm. (11 Mar 1998) |
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| plus lens | A converging lens. Synonym: plus lens. (05 Mar 2000) |
| plus strand | See: replicative form. (05 Mar 2000) |
| fluorescence plus Giemsa stain | <technique> A stain used to demonstrate sister chromatid exchange; cells are grown in 5-bromodeoxyuridine, followed by chromosome preparation, staining in Hoechst 33258, exposure to light, and staining in Giemsa; chromosomes exhibit a "harlequin" appearance. (05 Mar 2000) |
| anti-HIV agents | Agents used to treat aids and/or stop the spread of the HIV infection. These do not include drugs used to treat symptoms or opportunistic infections associated with aids. (12 Dec 1998) |
| receptors, HIV | Cellular receptors that bind the human immunodeficiency virus that causes aids. Included are CD4 antigens, found on t4 lymphocytes, and monocytes/macrophages, which bind to the HIV envelope protein gp120. (12 Dec 1998) |
| chronic symptomatic HIV infection | This refers to an HIV infection that is characterised by signs and symptoms of HIV that are not life-threatening. Examples include oral thrush, gingivitis, seborrheic dermatitis, molluscum contangiosum, fevers, fatigue, lymph node swelling, malaise and weight loss. This stage can be a signal for the conversion from asymptomatic HIV disease to HIV disease (moe pronouced symptoms include joint pains). AIDS is diagnosed after HIV disease has started to manifest life-threatening oppotunistic infections (for example pneumocystis, cryptosporidium, toxoplasmosis, etc). (27 Sep 1997) |
| middle stage HIV disease | <disease> This refers to an HIV infection that is characterised by signs and symptoms of HIV that are not life-threatening. Examples include oral thrush, gingivitis, seborrheic dermatitis, molluscum contangiosum, fevers, fatigue, lymph node swelling, malaise and weight loss. This stage can be a signal for the conversion from asymptomatic HIV disease to HIV disease (moe pronouced symptoms include joint pains). AIDS is diagnosed after HIV disease has started to manifest life-threatening oppotunistic infections (for example pneumocystis, cryptosporidium, toxoplasmosis, etc). (27 Sep 1997) |
| primary HIV infection | <infectious disease> The flu-like syndrome that oc immediately after a person contracts HIV. This mini infection precedes seroconversion and is characterised fever, sore throat, headache, skin rash and swollen glands. (06 Mar 1998) |
| HIV | <virology> A type of retrovirus (human immunodeficiency virus) that is responsible for the fatal illness acquired immunodeficiency syndrome. Two strains have been identified. Type 1: the retrovirus recognised as the agent that induces AIDS. Type 2: a virus closely related to HIV-1 that also leads to immune suppression. HIV-2 is not as virulent as HIV-1 and is epidemic only in West Africa. Acronym: HIV (11 Nov 1997) |
| HIV-1 | The type species of lentivirus and widely recognised as the aetiologic agent of acquired immunodeficiency syndrome (aids). It is characterised by its cytopathic effect and affinity for the t4-lymphocyte. (12 Dec 1998) |
| HIV-1 reverse transcriptase | <enzyme> HIV-1 enzyme responsible for the synthesis of DNA from genomic RNA of the virus. It is encoded by the pol gene of HIV-1. Registry number: EC 2.7.7.- (12 Dec 1998) |
| HIV-2 | An HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition. It shares serologic reactivity and sequence homology with the simian lentivirus siv and infects only t4-lymphocytes expressing the CD4 phenotypic marker. (12 Dec 1998) |
| HIV-2 protease | <enzyme> Processes hiv-1pr53(gag) and analogous junction peptides in vitro; less than 60% amino acid identity to hiv-1 protease Registry number: EC 3.4.23.- Synonym: hiv2 protease (26 Jun 1999) |
| HIV-2 reverse transcriptase | <enzyme> Responsible for synthesis of double-stranded DNA from the genomic RNA of the virus; has rnase h and DNA-dependent DNA polymerase activities; was indexed as reverse transcriptase (87-91) Registry number: EC 2.7.7.- (26 Jun 1999) |