| guanfacine | <chemical> A centrally acting antihypertensive agent. The drug lowers both systolic and diastolic blood pressure by activating the central nervous system alpha-2 adrenoreceptors, which results in reduced sympathetic outflow leading to reduced vascular tone. Its adverse reactions include dry mouth, sedation, and constipation. Pharmacological action: adrenergic alpha-agonists, antihypertensive agents, sympatholytics. Chemical name: Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro- (12 Dec 1998) |
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