| gout | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
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| gout arthritis | <rheumatology> Recurrent acute arthritis of peripheral joints caused by the accumulation of monosodium urate crytals. Often presents as pain and swelling confined to one joint. The big toe joint is commonly affected. The arthritis occurs secondary to an inherited abnormality of purine metabolism, resulting in the deposition of uric acid crystals (sodium urate) within the joint space and articular cartilage. Usually due to overproduction of uric acid but may be a result of under excretion. The problems partly arise because neutrophils release lysosomal enzymes as a result of damage to the phagosome membrane by ingested crystals: colchicine acts to reduce the attack by inhibiting lysosome phagosome fusion. (18 Nov 1997) |
| gout diet | A diet containing a minimal quantity of purine bases (meats); liver, kidney, and sweetbread especially are excluded and replaced by dairy products, fruits, and cereals; alcoholic beverages also are excluded. Synonym: purine-free diet. (05 Mar 2000) |
| gout suppressants | Agents that increase uric acid excretion by the kidney (uricosuric agents), decrease uric acid production (antihyperuricaemics), or alleviate the pain and inflammation of acute attacks of gout. (12 Dec 1998) |
| gout, tophaceous | A form of chronic gout. Nodular masses of uric acid crystals (tophi) are deposited in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord! (12 Dec 1998) |
| goutwort | <botany> A coarse umbelliferous plant of Europe (aegopodium Podagraria). Synonym: bishop's weed, ashweed, and herb gerard. Origin: So called from having been formerly used in assuaging the pain of the gout. Source: Websters Dictionary (01 Mar 1998) |
| gouty | 1. Diseased with, or subject to, the gout; as, a gouty person; a gouty joint. 2. Pertaining to the gout. "Gouty matter." 3. Swollen, as if from gout. 4. Boggy; as, gouty land. Gouty bronchitis, bronchitis arising as a secondary disease during the progress of gout. Gouty concretions, calculi (urate of sodium) formed in the joints, kidneys, etc, of sufferers from gout. Gouty kidney, an affection occurring during the progress of gout, the kidney shriveling and containing concretions of urate of sodium. Source: Websters Dictionary (01 Mar 1998) |
| gouty arthritis | An attack that is usually extremely painful of joint inflammation due to deposits of uric acid crystals in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals, causing pain, heat, and redness of the joint tissues. The term gout commonly is used to refer to these painful arthritis attacks but gouty arthritis is only one manifeatation of gout. (12 Dec 1998) |
| gouty diathesis | A state of susceptibility to attacks of gout or development of tophi, usually associated with hyperuricaemia or hyperexcretion of urate in urine. (05 Mar 2000) |
| gouty pearl | A concretion of sodium urate on the cartilage of the ear, occurring in the gouty. (05 Mar 2000) |
| gouty urine | Urine of a high colour containing uric acid in excess. (05 Mar 2000) |
| arthritis, gout | Joint inflammation caused by uric acid crystal deposits in the joint space An attack is usually extremely painful.The uric acid crystals are deposited in the joint fluid (synovial fluid) and joint lining (synovial lining). Intense joint inflammation occurs as white blood cells engulf the uric acid crystals, causing pain, heat, and redness of the joint tissues. The term gout commonly is used to refer to these painful arthritis attacks but gouty arthritis is only one manifeatation of gout. (12 Dec 1998) |
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| calcium gout | <rheumatology> Chondrocalcinosis, chronic recurrent arthritis clinically similar to gout. (27 Sep 1997) |
| masked gout | latent gout |
| retrocedent gout | An obsolete term for the occurrence of severe gastric, cardiac, or cerebral symptoms during an attack of gout, especially when the joint and other symptoms suddenly subside at the same time. Saturnine gout, gout occurring in a person with lead poisoning. Synonym: lead gout. Secondary gout, gout resulting from increased serum uric acid levels as a result of an antecedent disease, such as a proliferative disease of the blood and bone marrow, lead poisoning, or prolonged chronic renal failure (on dialysis). Tophaceous gout, gout in which deposits of uric acid and urates occur as gouty tophi. (05 Mar 2000) |
| primary gout | Acute episodes of crystal-induced synovitis due to abnormality of purine metabolism; lower than normal urinary excretion of urate leading to hyperuricaemia and acute episodes of joint inflammation. Synonym: primary gout. Interval gout, an asymptomatic phase between acute attacks of gout. Latent gout, hyperuricaemia without symptoms of gout. Often used synonymously with interval gout. Synonym: masked gout. (05 Mar 2000) |
| idiopathic gout | Acute episodes of crystal-induced synovitis due to abnormality of purine metabolism; lower than normal urinary excretion of urate leading to hyperuricaemia and acute episodes of joint inflammation. Synonym: primary gout. Interval gout, an asymptomatic phase between acute attacks of gout. Latent gout, hyperuricaemia without symptoms of gout. Often used synonymously with interval gout. Synonym: masked gout. (05 Mar 2000) |
| tophaceous gout | Nodular masses of uric acid crystals (tophi) are deposited in different soft tissue areas of the body. Even though tophi are most commonly found as hard nodules around the fingers, at the tips of the elbows, and around the big toe, tophi nodules can appear anywhere in the body. They have been reported in unexpected areas such as in the ears, vocal cords, or around the spinal cord! tophaceous gout is always a result of chronic gout. (12 Dec 1998) |
| lead gout | saturnine gout |