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vasculitis <pathology> Inflammation of a vessel, angiitis.
Origin: L. Vasculum = vessel
(18 Nov 1997)
vasculitis, allergic cutaneous Vasculitis due to allergic reaction, marked by such cutaneous lesions as papules, macules, vesicles, urticarial wheals, purpura, and small ulcers, and accompanied by itching and usually a slight fever and malaise.
(12 Dec 1998)
vasculitis, hypersensitivity Heterogeneous group of disorders characterised by a vasculitic syndrome presumed to be associated with a hypersensitivity reaction following exposure to an antigen such as an infectious agent, a drug, or other foreign or endogenous substance.
(12 Dec 1998)
cutaneous vasculitis An acute form of vasculitis which may affect the skin only, but also may involve other organs, with a polymorphonuclear infiltrate in the walls of and surrounding small (dermal) vessels. Nuclear fragments are formed by karyorrhexis of the neutrophils.
See: leukocytoclastic vasculitis.
Synonym: allergic angiitis, hypersensitivity vasculitis.
(05 Mar 2000)
hypersensitivity vasculitis An acute form of vasculitis which may affect the skin only, but also may involve other organs, with a polymorphonuclear infiltrate in the walls of and surrounding small (dermal) vessels. Nuclear fragments are formed by karyorrhexis of the neutrophils.
See: leukocytoclastic vasculitis.
Synonym: allergic angiitis, hypersensitivity vasculitis.
(05 Mar 2000)
hypocomplementemic vasculitis Cutaneous lesions resembling urticaria but lasting more than 24 hours, with biopsy findings of leukocytoclastic vasculitis and variable systemic changes, usually with hypocomplementemia.
Synonym: hypocomplementemic vasculitis.
(05 Mar 2000)
nodular vasculitis Chronic or recurrent nodular lesions of subcutaneous tissue, especially of the legs of older women, with lobular panniculitis, granulomatous inflammation with multinucleated giant cells, focal necrosis, and obliterative inflammation of the small blood vessels, resembling erythema induratum but without evidence of associated tuberculosis.
(05 Mar 2000)
urticarial vasculitis Cutaneous lesions resembling urticaria but lasting more than 24 hours, with biopsy findings of leukocytoclastic vasculitis and variable systemic changes, usually with hypocomplementemia.
Synonym: hypocomplementemic vasculitis.
(05 Mar 2000)
leukocytoclastic vasculitis Cutaneous acute vasculitis characterised clinically by palpable purpura, especially of the legs, and histologically by exudation of the neutrophils and sometimes fibrin around dermal venules, with nuclear dust and extravasation of red cells; may be limited to the skin or involve other tissues as in Henoch-Schonlein purpura.
See: cutaneous vasculitis.
Origin: G. Leukos, white, + kytos, cell, + klastos, broken, fr. Klao, to break
(05 Mar 2000)
livedo vasculitis Hyaline degeneration of the walls of small dermal blood vessels with occlusion seen with cryoglobulinaemia or in atrophie blanche.
(05 Mar 2000)
acrocephalosyndactyly type 1 <paediatrics> An inherited disease (autosomal dominant) or a spontaneously occurring disease characterised by a peaked head and unusual facial appearance, due to the premature closure of the cranial sutures.
A skull X-ray can confirm the diagnosis and treatment is surgical.
Inheritance: autosomal dominant.
(27 Sep 1997)
Alzheimer type I astrocyte Enlarged frequently multinucleated astrocytes, seen in progressive multifocal leukoencephalopathy.
(05 Mar 2000)
Alzheimer type II astrocyte Enlarged astrocytes with vesicular nuclei and one or more small basophilic nucleoli, seen in hepatocerebral disease and Wilson's disease.
(05 Mar 2000)
American Type Culture Collection <cell culture> A key resource for cultured cells, located in Rockville, USA.
(12 Dec 1998)
Antoni type A neurilemoma <tumour> Relatively solid or compact arrangement of neoplastic tissue that consists of Schwann cells arranged in twisting bundles and associated with delicate reticulin fibres; the nuclei of the Schwann cells are frequently grouped in parallel rows (so-called palisades), and the nuclei and fibres sometimes form exaggerated tactile corpuscles, called Verocay bodies.
(05 Mar 2000)
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