| Gierke's disease | Glycogenosis due to glucose-6-phosphatase deficiency, resulting in accumulation of excessive amounts of glycogen of normal chemical structure, particularly in liver and kidney. Synonym: Gierke's disease, glucose-6-phosphatase hepatorenal glycogenosis, von Gierke's disease. (05 Mar 2000) |
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| Von Gierke's disease | <disease> A congenital disease caused by a metabolic error in which the body deposits an abnormally high amount of glycogen in the kidneys and liver, the disease produces symptoms such as hypoglycaemia (low blood sugar) and hyperlipaemia (an excess of lipid molecules in the blood, which can lead to problems such as clogged arteries and heart attacks). (09 Oct 1997) |
| Gierke cells | Small cells characteristic of the substantia gelatinosa (lamina II) of the dorsal horn of the spinal cord. (05 Mar 2000) |
| Gierke, Edgar von | <person> German pathologist, 1877-1945. See: Gierke's disease, von Gierke's disease. (05 Mar 2000) |
| Gierke, Hans | <person> German anatomist, 1847-1886. See: Gierke's respiratory bundle. (05 Mar 2000) |
| Gierke's respiratory bundle | A slender, compact fibre bundle extending longitudinally through the dorsolateral region of the medullary tegmentum, surrounded by the nucleus of the solitary tract, below the obex decussating over the central canal, and descending over some distance into the upper cervical segments of the spinal cord. It is composed of primary sensory fibres that enter with the vagus, glossopharyngeal, and facial nerves, and in part convey information from stretch receptors and chemoreceptors in the walls of the cardiovascular, respiratory, and intestinal tracts; in rostral parts of the tract impulses are generated by the receptor cells of the taste buds in the mucosa of the tongue. Its fibres are distributed to the nucleus of the solitary tract. Synonym: tractus solitarius, fasciculus rotundus, fasciculus solitarius, funiculus solitarius, Gierke's respiratory bundle, Krause's respiratory bundle, round fasciculus, solitary bundle, solitary fasciculus. (05 Mar 2000) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| acute disease | Disease having a short and relatively severe course. (12 Dec 1998) |
| Adams-Stokes disease | <syndrome> Transient asystole or ventricular fibrillation in the presence of atrioventricular block. (12 Dec 1998) |
| Addison-Biermer disease | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| Addison's disease | <endocrinology> A rare endocrine disease that results from the underproduction of aldosterone and cortisol (hormones) by the adrenal glands. Symptoms include weakness, low blood pressure, anaemia, low blood sugar and electrolyte abnormalities. (27 Sep 1997) |