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GAWTS genomic amplification with transcript sequencing
gDNA genomic deoxyribonucleic acid
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CGH Comparative Genomic Hybridisation
gDNA Genomic DNA
GISH Genomic in situ hybridization
RLGS Restriction Landmark Genomic Scanning
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genomic Relating to a genome.
(05 Mar 2000)
genomic DNA <molecular biology> The DNA which is found in the organisms genome and is passed on to offspring as information necessary for survival. The phrase is used to distinguish between other types of DNA, such as found within plasmids.
(09 Oct 1997)
genomic formula <molecular biology> The method used to identify the number of sets of chromosomes within a cell or organism (i.e. Its ploidy). Each set is designated n so one set is n is haploid, two sets is 2n is diploid, three sets is 3n is triploid, four sets is 4n is tetraploid, etc. Also, 2n+1 is known as trisomy (i.e. Two full sets plus a third copy of one of the chromosomes).
(09 Oct 1997)
genomic imprinting <genetics, molecular biology> Parent specific expression or repression of genes or chromosomes in offspring. There are an increasing number of recognised chromosomal imprinting events in pathological conditions: for example preferential transmission of paternal or maternal predisposition to diabetes or atopy, preferential retention of paternal alleles in rhabdomyosarcoma, osteosarcoma, retinoblastoma and Wilm's tumour, preferential translocation to the paternal chromosome 9 of a portion of maternal chromosome 22 to form the Philadelphia chromosome of chronic myeloid leukaemia.
(18 Nov 1997)
genomic library <molecular biology> A collection of DNA molecules, derived from restriction fragments that have been cloned in vectors, that includes all or part of the genetic material of an organism.
(18 Nov 1997)
library, genomic A collection of DNA clones made from a set of randomly generated overlapping DNA fragments representing the entire genome of an organism. As a molecular genetic sequel to john steinbeck's of mice and men , today you can have a mouse genomic library or a human genomic library.
(12 Dec 1998)
atlantic islands Widely scattered islands in the atlantic ocean as far north as the azores and as far south as the south sandwich islands, with the greatest concentration found in the caribbean region. They include annobon island, ascension, canary islands, falkland islands, fernando po (also called isla de bioko and bioko), gough island, madeira, sao tome and principe, saint helena, and tristan da cunha.
(12 Dec 1998)
pacific islands The islands of the pacific ocean divided into micronesia, melanesia, and polynesia (including new zealand). The collective name oceania includes the aforenamed islands, adding Australia, new zealand, and the malay archipelago (indonesia).
(12 Dec 1998)
pancreatic islands <anatomy> Groups of cells found within the pancreas: A cells and B-cells secrete insulin and glucagon.
See: D cells.
(18 Nov 1997)
virgin islands of the united states A group of islands in the lesser antilles in the west indies, the three main islands being st. Croix, st. Thomas, and st. John. The capital is charlotte amalie. The virgin islands were discovered by columbus in 1493. Before 1917 the u.s. Virgin islands were held by the danish and called the danish west indies but the name was changed when the united states acquired them by purchase. Virgin refers to the fact that columbus made his discovery on st. Ursula's day - virgins being her legendary companions - or to the resemblance of the chain of islands to a procession of nuns or virgins.
(12 Dec 1998)
mediterranean islands Scattered islands in the mediterranean sea. The chief islands are the balearic islands (belong to spain; majorca and minorca are among these), corsica (belongs to france), crete (belongs to greece), cyprus (a republic), the cyclades, dodecanese and ionian islands (belong to greece), malta (a republic), sardinia and sicily (belong to italy).
(12 Dec 1998)
channel islands A group of four british islands and several islets in the english channel off the coast of france. They are known to have been occupied prehistorically. They were a part of normandy in 933 but were united to the british crown at the time of the norman conquest in 1066. Guernsey and jersey originated noted breeds of cattle.
(12 Dec 1998)
cpg islands Areas of increased density of the dinucleotide sequence guanine--phosphate diester--cytosine. They form stretches of DNA several hundred base pairs long and number about 30,000 islands in the mammalian genome. They are unmethylated and the site of frequent mutations. Many of the genes with which the islands are associated are housekeeping genes that are constitutively expressed.
(12 Dec 1998)
indian ocean islands Numerous islands in the indian ocean situated east of madagascar, north to the arabian sea and east to sri lanka. Included are comoros (republic), madagascar (republic), maldives (republic), mauritius (parliamentary democracy), pemba (administered by tanzania), reunion (a department of france), and seychelles (republic).
(12 Dec 1998)
islands of Calleja Dense clusters of very small nerve cells (granule cells) characteristic of the olfactory tubercle at the base of the forebrain.
(05 Mar 2000)
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  • Genomic Islands - »õâ Distinct units in some bacterial, bacteriophage or plasmid GENOMES that are types of MOBILE GENETIC ELEMENTS. Encoded in them are a variety of fitness conferring genes, such as VIRULENCE FACTORS (in "pathogenicity islands or islets"), ANTIBIOTIC RESISTANCE genes, or genes required for SYMBIOSIS (in "symbiosis islands or islets"). They range in size from 10 - 500 kilobases, and their GC CONTENT and CODON usage differ from the rest of the genome. They typically contain an INTEGRASE gene, although in some cases this gene has been deleted resulting in "anchored genomic islands".
    Synonyms : Anchored Genomic Islands, Genomic Islets, Pathogenicity Islets, Symbiosis Islands, Symbiosis Islets, Anchored Genomic Island, Genomic Island, Genomic Island, Anchored, Genomic Islands, Anchored, Genomic Islet, Island, Anchored Genomic, Island, Genomic
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