| supplement | Something that supplies a want or make an addition: something that completes, adds a finishing touch or brings closer to completion or a desired state. (18 Nov 1997) |
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| classical epidemiology | <epidemiology> Our term for the varieties of epidemiology primarily concerned with the statistical relationships between disease agents, both infectious and non-infectious; for example a study to establish the relative risk of lung cancer associated with smoking. We contrast this with ecological epidemiology. (05 Dec 1998) |
| clinical epidemiology | The field concerned with applying epidemiological principles in a clinical setting.Whereas classical epidemiology studies populations in an attempt to assess causes and distribution of disease and to formulate statistical measures of risk, clinical epidemiology focuses on medically defined populations (patients). (05 Mar 2000) |
| ecological epidemiology | <epidemiology> A branch of epidemiology which views disease as a result of the ecological interactions between populations of hosts and parasites; what we do. We contrast this with classical epidemiology. (05 Dec 1998) |
| epidemiology | <study> The study of the distribution and determinants of health-related states and events in populations and the control of health problems, the study of epidemic disease. (27 Sep 1997) |
| epidemiology, classical | The study of populations in order to determine the frequency and distribution of disease and measure risks. (12 Dec 1998) |
| epidemiology, clinical | Epidemiology focused specifically upon patients. (12 Dec 1998) |
| epidemiology, molecular | The application of molecular biology to the answering of epidemiological questions. The examination of patterns of changes in DNA to implicate particular carcinogens and the use of molecular markers to predict which individuals are at highest risk for a disease are common examples. (12 Dec 1998) |
| genetic | <biology> Pertaining to reproduction or to birth or origin. (07 May 1998) |
| genetic amplification | A process for producing an increase in pertinent genetic material, particularly for increasing the proportion of plasmid DNA to that of bacterial DNA. Includes the production of extrachromosomal copies of the genes for RNA. (05 Mar 2000) |
| genetic assimilation | <genetics> A situation in which a characteristic that is normally expressed only in certain environmental situations becomes fixed in a population so that it no longer requires environmental factors to be expressed. (07 May 1998) |
| genetic association | The occurrence together in a population, more often than can be readily explained by chance, of two or more traits of which at least one is known to be genetic. (05 Mar 2000) |
| genetic block | <biochemistry, molecular biology> An obstruction in a biochemical pathway caused by a mutation that has crippled production of an enzyme critical to the pathway. (07 May 1998) |
| genetic burden | The genetic debt due to harmful mutation but as yet undischarged. (In a large population of fixed size every mutation with diminished genetic fitness will eventually become extinct and depending on the details of inheritance and phenotype must be paid for by a fixed number of genetic deaths per mutation, the genetic debt.) (05 Mar 2000) |
| genetic carrier | An unaffected heterozygote bearing a usually harmful recessive gene, a cancer that bears a dominant but latent age-dependent trait to have offspring with unbalanced karyotypes. (05 Mar 2000) |