| Gamna's disease | <disease> A form of chronic splenomegaly characterised by conspicuous thickening of the capsule and the presence of multiple, small, rustlike, brown foci (Gamna-Gandy bodies), which contain iron; this condition may be observed in fibrocongestive splenomegaly, sickle cell disease, and some examples of haemochromatosis. (05 Mar 2000) |
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| Gamna | Carlos, Italian physician, 1896-1950. See: Gamna's disease, Gamna-Favre bodies, Gandy-Gamna bodies, Gamna-Gandy bodies, Gamna-Gandy nodules. (05 Mar 2000) |
| Gamna-Favre bodies | Characteristic, relatively large, intracytoplasmic basophilic inclusion body's observed in endothelial cells in lymphogranuloma venereum; probably composed of degenerated nuclear material. See: Miyagawa bodies. (05 Mar 2000) |
| Gamna-Gandy bodies | Small firm spheroidal or irregular foci that are yellow-brown, brown, or rustlike in colour, occurring chiefly in the spleen in such conditions as congestive splenomegaly and sickle cell disease, and consisting of relatively dense fibrous tissue or collagenous fibres impregnated with iron pigment and calcium salts; probably result from organization and scarring of sites where small perivascular haemorrhages occurred. Synonym: Gamna-Gandy nodules, Gandy-Gamna bodies, siderotic nodules. (05 Mar 2000) |
| Gamna-Gandy nodules | Small firm spheroidal or irregular foci that are yellow-brown, brown, or rustlike in colour, occurring chiefly in the spleen in such conditions as congestive splenomegaly and sickle cell disease, and consisting of relatively dense fibrous tissue or collagenous fibres impregnated with iron pigment and calcium salts; probably result from organization and scarring of sites where small perivascular haemorrhages occurred. Synonym: Gamna-Gandy nodules, Gandy-Gamna bodies, siderotic nodules. (05 Mar 2000) |
| Gandy-Gamna bodies | Small firm spheroidal or irregular foci that are yellow-brown, brown, or rustlike in colour, occurring chiefly in the spleen in such conditions as congestive splenomegaly and sickle cell disease, and consisting of relatively dense fibrous tissue or collagenous fibres impregnated with iron pigment and calcium salts; probably result from organization and scarring of sites where small perivascular haemorrhages occurred. Synonym: Gamna-Gandy nodules, Gandy-Gamna bodies, siderotic nodules. (05 Mar 2000) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |
| acute disease | Disease having a short and relatively severe course. (12 Dec 1998) |
| Adams-Stokes disease | <syndrome> Transient asystole or ventricular fibrillation in the presence of atrioventricular block. (12 Dec 1998) |
| Addison-Biermer disease | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| Addison's disease | <endocrinology> A rare endocrine disease that results from the underproduction of aldosterone and cortisol (hormones) by the adrenal glands. Symptoms include weakness, low blood pressure, anaemia, low blood sugar and electrolyte abnormalities. (27 Sep 1997) |