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gp120 <protein, virology> A glycoprotein from HIV's envelope that binds to the CD4 molecules on cells outside membrane.
Free gp120 in the body may be toxic to cells on its own, causing CD4 cell depletion in the immune system through apoptosis and neurological damage leading to AIDS dementia complex.
(09 Oct 1997)
gp160 processing protease <enzyme> Converts hiv gp160 to gp120 and gp41, cleaving between arg511 and ala512
Registry number: EC 3.4.99.-
(26 Jun 1999)
gp4l <protein, virology> A glycoprotein from HIV's outside envelope that complexes with gp120 to form the mechanism enabling HIV to latch onto and enter cells.
(09 Oct 1997)
GPI An index of gingivitis, gingival irritation, and advanced periodontal disease.
(05 Mar 2000)
GPI anchor <biochemistry, molecular biology> Common modification of the C terminus of membrane attached proteins in which a phosphatidyl inositol moiety is linked through glucosamine and mannose to a phosphoryl ethanolamine residue that is linked to the C terminal amino acid of the protein by its amino group.
Glypiation is the sole means of attachment of such proteins to the membrane. The name comes from the addition of glycosyl phosphatidyl inositol (PI).
(18 Nov 1997)
GPT alanine aminotransferase
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