| GMP | A major component of ribonucleic acids. Synonym: guanine ribonucleotide, guanosine 5'-monophosphate. Guanylic acid reductase (GMP reductase), an enzyme that catalyses the reaction of GMP with NADPH producing IMP, NH3, and NADP+; a part of the purine salvage pathway. Guanylic acid synthetase (GMP synthetase), an enzyme catalyzing the reaction of l-glutamine, XMP, and ATP to produce GMP, l-glutamate, AMP, and pyrophosphate; a key step in purine biosynthesis. Acronym: GMP (05 Mar 2000) |
|---|---|
| GMP reductase | <abbreviation> Guanylic acid reductase. (05 Mar 2000) |
| GMP synthetase | <enzyme> Consider also GMP synthetase (glutamine hydrolysing) EC 6.3.5.2 Registry number: EC 6.3.4.1 (26 Jun 1999) |
| cyclic GMP | <molecular biology> 3'5' cyclic ester of GMP. A second messenger generated by guanylyl cyclase. See: ANP, Nitric oxide. (18 Nov 1997) |
|---|---|
| cyclic GMP-dependent protein kinases | <enzyme> A group of enzymes that are dependent on cyclic GMP and catalyses the phosphorylation of serine or threonine residues of proteins. Registry number: EC 2.7.10.- (12 Dec 1998) |
| cyclic GMP sensitive 3'-exoribonuclease | <enzyme> Degradation of newly synthesised RNA in cells of bacillus brevis is mediated primarily by above enzyme Registry number: EC 3.1.14.- Synonym: cgmp-exoribonuclease (26 Jun 1999) |
| dibutyryl cyclic GMP | <chemical> N-(1-oxobutyl)-cyclic 3',5'-(hydrogen phosphate)-2'-butanoate guanosine. A derivative of cyclic GMP. It has a higher resistance to extracellular and intracellular phosphodiesterase than cyclic GMP. Chemical name: Guanosine, N-(1-oxobutyl)-, cyclic 3',5'-(hydrogen phosphate) 2'-butanoate (12 Dec 1998) |
| 3',5'-cyclic-GMP phosphodiesterase | <enzyme> An enzyme that catalyses the hydrolysis of cyclic GMP to yield guanosine-5'-phosphate. Chemical name: 3',5'-Cyclic-GMP 5'-nucleotidohydrolase Registry number: EC 3.1.4.35 (12 Dec 1998) |