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GABA Gamma-Amino-Butyric Acid
GABA, gaba gamma-aminobutyric acid
GABAT, GABA-T gamma-aminobutyric acid transaminase
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GABA 3H-gamma aminobutyric acid
GABA 4-Amino-n-butyric acid
GABA gamma-amino butyric acidA
GABA Gamma-aminobutyrate
GABA Gamma-aminobutyric
GABA(A) GABA type A
GABA(A) gamma-amino-n-butyric acid
GABA(A) gamma-aminobutylic acid A
GABA(A)-R GABA(A) receptor
GABA(A)R gamma-aminobutyric acid A receptor
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[(3)H]-GABA 3)H]-gamma-aminobutyric acid
GAT1 GABA transporter
GWS GABA Withdrawal Syndrome
IR GABA)-immunoreactive
ICl GABA)-induced Cl- current
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  • GABA A receptors
    GABA A ¼ö¿ëü(áôé»ô÷)
  • GABA receptors
    GABA ¼ö¿ëü(áôé»ô÷)
  • GABA=> gamma aminobutyric acid
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  • GABAB receptors
    GABA B ¼ö¿ëü(áôé»ô÷)
  • GABAergic
    GABA¼ºÀÇ, GABAÀۿ뼺ÀÇ.
  • GABAmimetic
    GABAÀ¯»ç¾à, GABA¾ç ÀÛ¿ëÀÇ.
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  • gamma amino butyric acid =GABA
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  • GABA shunt
    GABA ºÐ·Î(ÝÂÖØ)
  • GABAergic neuron
    GABAÀÛµ¿¼º(íÂÔÑàõ) ½Å°æ¿ø(ãêÌèê«)
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GABA <biochemistry> An important amino acid which functions as the most prevalent inhibitory neurotransmitter in the central nervous system.
Gamma aminobutyric acid works in partnership with a derivative of Vitamin B-6, pyridoxine, to cross from the axons to the dendrites through the synaptic cleft, in response to an electrical signal in the neuron and inhibits message transmission. This helps control the nerve cells from firing too fast, which would overload the system.
The action of gamma aminobutyric acid decreases epileptic seizures and muscle spasms by inhibiting electrical signals in this manner. Studies have shown that the site of action in the brain of benzodiazepams, including Valium, is directly coupled to the brain receptor for gamma aminobutyric acid.
Acronym: GABA
(05 Jan 1998)
gaba agents Substances used for their pharmacological actions on gabaergic systems. Gabaergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
(12 Dec 1998)
gaba agonists Drugs that bind to and activate gaba receptors (receptors, gaba).
(12 Dec 1998)
gaba antagonists Drugs that bind to but do not activate gaba receptors, thereby blocking the actions of endogenous gaba or gaba agonists.
(12 Dec 1998)
GABA dehydrogenase <enzyme> From crude mitochondrial fraction of rat brain; reported first product is gamma-aminocrotonic acid; p-iodonitrotetrazolium violet can serve as acceptor of electrons
Registry number: EC 1.-
(26 Jun 1999)
gaba modulators Substances that do not act as agonists or antagonists but do affect the gaba receptor-ionophore complex. Gaba-a receptors (receptors, gaba-a) appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gaba-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. General anaesthetics probably act at least partly by potentiating gabaergic responses, but they are not included here.
(12 Dec 1998)
GABA pathway The pathway that ultimately converts 4-aminobutyrate to succinate; succinate is then converted to alpha-ketoglutarate, via the tricarboxylic acid cycle, which is then acted upon by glutamate dehydrogenase; glutamate is then decarboxylated to reform 4-aminobutyrate; an important pathway for those cells which make this neuroactive molecule.
Synonym: GABA pathway.
(05 Mar 2000)
GABA permease <chemical> From aspergillus nidulans; uga4 is from saccharomyces cerevisiae
Synonym: gamma-amino-n-butyrate permease, 4-aminobutyric acid permease, uga4 protein, uga4 gene product
(26 Jun 1999)
GABA receptor <physiology> Ligand gated chloride ion channel forming receptor opened by gamma aminobutyric acid. Two distinct types: A and B.
A receptor: One of a family of neurotransmitter receptors with fast intrinsic ion channels that includes the glycine receptor and the nicotinic acetylcholine receptor. Distinct from another major receptor family, the muscarininc acetylcholine receptor and rhodopsin, with no intrinsic ion channel. The A receptor is specifically blocked by bicuculline. It consists of two pairs of protein chains forming an A2B2 complex, the A chains bind benzodiazepine and the B chains bind GABA. The 4 subunits are thought to form a tight group with the chloride channel in the middle. There is considerable similarity between the amino acid sequences of the receptor subunits and those of the nicotinic acetylcholine receptor suggesting that both receptors are derived from some evolutionary ancestor.
See: amino acid receptor superfamily.
B receptor: Brain receptor (80 kD) for the inhibitory neurotransmitter gamma amino butyric acid. Differs from the A receptor both in agonist specificity (baclofen is a specific agonist) and its effects on cells. It modulates intracellular calcium levels through a Go mediated effect on N type calcium channels and also lowers intracellular cAMP levels by an effect on adenylyl cyclase, thereby reducing the secretion of catecholamines.
(05 Jan 1998)
gabase <chemical> Mixture of 4-aminobutyrate transaminase (EC 2.6.1.19) and succinate saemialdehyde dehydrogenase (nadp) (EC 1.2.1.16) from pseudomonas fluorescens; used in assay of gaba
(26 Jun 1999)
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receptors, gaba Cell-surface proteins that bind gaba with high affinity and trigger changes that influence the behaviour of cells. Gaba-a receptors control chloride channels formed by the receptor complex itself. They are blocked by bicuculline and usually have modulatory sites sensitive to benzodiazepines and barbiturates. Gaba-b receptors act through g-proteins on several effector systems, are insensitive to bicuculline, and have a high affinity for l-baclofen.
(12 Dec 1998)
receptors, gaba-a Cell surface proteins which bind gaba and control an integral membrane chloride channel. Gaba-a receptors are the most prevalent inhibitory neurotransmitter receptors in the brain. Several isoforms have been cloned, and they belong to a superfamily which includes nicotinic receptors, glycine receptors, and 5ht-3 receptors. Most gaba-a receptors have separate modulatory sites sensitive to benzodiazepines and to barbiturates.
(12 Dec 1998)
receptors, gaba-b Cell surface proteins which bind gaba and influence cells via interactions with g-proteins. Gaba-b receptors are pharmacologically characterised by their insensitivity to the blocker bicuculline and sensitivity to the agonist l-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase a2, activation of potassium channels, and inactivation of voltage-activated calcium channels.
(12 Dec 1998)
MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 1
  • GABA Agents - »õâ Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function.
    Synonyms : GABAergic Agent, GABAergic Agents, Acid Agents, gamma-Aminobutyric, Agent, GABAergic, Agents, GABA, Agents, GABAergic, Agents, gamma-Aminobutyric Acid, gamma Aminobutyric Acid Agents
  • GABA Agonists - »õâ Drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA).
    Synonyms : GABA Agonist, GABA Receptor Agonist, GABA Receptor Agonists, gamma-Aminobutyric Acid Agonist, Acid Agonist, gamma-Aminobutyric, Acid Agonists, gamma-Aminobutyric, Agonist, GABA, Agonist, GABA Receptor, Agonist, gamma-Aminobutyric Acid, Agonists, GABA
  • GABA Antagonists - »õâ Drugs that bind to but do not activate GAMMA-AMINOBUTYRIC ACID receptors, thereby blocking the actions of endogenous GAMMA-AMINOBUTYRIC ACID or GAMMA-AMINOBUTYRIC ACID agonists.
    Synonyms : GABA Antagonist, GABA Receptor Antagonists, Acid Antagonists, gamma-Aminobutyric, Antagonist, GABA, Antagonists, GABA, Antagonists, GABA Receptor, Antagonists, gamma-Aminobutyric Acid, Receptor Antagonists, GABA, gamma Aminobutyric Acid Antagonists
  • GABA Modulators - »õâ Substances that do not act as agonists or antagonists but do affect the GAMMA-AMINOBUTYRIC ACID receptor-ionophore complex. GABA-A receptors (RECEPTORS, GABA-A) appear to have at least three allosteric sites at which modulators act: a site at which BENZODIAZEPINES act by increasing the opening frequency of GAMMA-AMINOBUTYRIC ACID-activated chloride channels; a site at which BARBITURATES act to prolong the duration of channel opening; and a site at which some steroids may act. GENERAL ANESTHETICS probably act at least partly by potentiating GABAergic responses, but they are not included here.
    Synonyms : GABAergic Modulators, Acid Modulators, gamma-Aminobutyric, Modulators, GABA, Modulators, GABAergic, Modulators, gamma-Aminobutyric Acid, gamma Aminobutyric Acid Modulators
  • GABA Plasma Membrane Transport Proteins - »õâ A family of plasma membrane neurotransmitter transporter proteins that regulates that extracellular levels of the inhibitory neurotransmitter GAMMA-AMINOBUTYRIC ACID. They differ from GABA RECEPTORS, which signal cellular responses to GAMMA-AMINOBUTYRIC ACID. They control GABA reuptake into PRESYNAPTIC TERMINALS in the CENTRAL NERVOUS SYSTEM through high-affinity sodium-dependent transport.
    Synonyms : GABA Plasma Membrane Transporter Proteins, GABA Transporter 1, GABA Transporter 2, GABA Transporter 3, GABA Transporter 4, GABA Transporters, GAT-1 Transporter, GAT-2 Transporter, GAT-3 Transporter, GAT-4 Transporter, GAT1 Transporter, GAT2 Transporter
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GABA gamma aminobutyric acid: an amino acid that is found in the central nervous system; acts as an inhibitory neurotransmitter
Ãâó: wordnet.princeton.edu/perl/webwn
GABA Gamma-aminobutyric acid (GABA) is a neurotransmitter in widely divergent species. In humans, GABA acts at inhibitory synapses in the brain and spinal cord. As in the other contexts where GABA acts as a transmitter, the inhibition results from a hyperpolarization of the transmembrane potential of the inhibited neuron, which is elicited by the binding of GABA molecules to specific receptors in the plasma membrane of both pre- and post-synaptic cells. ...
Ãâó: en.wikipedia.org/wiki/GABA
GABA ): The major inhibitory neurotransmitter in the brain.
Ãâó: science.education.nih.gov/supplements/nih2/addicti...
GABA a chemical messenger in the brain, spinal cord, heart, lungs, and kidneys, which sends messages telling the body to slow down. GABA is the primary inhibitory neurotransmitter in the brain.
Ãâó: www.dbs-stn.org/glossary1.asp
gabapentin A substance that is being studied as a treatment for relieving hot flashes in women with breast cancer. It belongs to the family of drugs called anticonvulsants.
Ãâó: goldbamboo.com/glossary-1g.html
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    gamma-aminobutyricacid;°¨¸¶¾Æ¹Ì³ë ³«»ê(Æ÷À¯·ùÀÇ ÁßÃ߽Ű濡 »ý±â´Â ¾Æ¹Ì³ë»ê)
  • Gabar
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  • gabardine
    °³¹öµò(´ÉÁ÷ ¹æ¼ö º¹Áö);°³¹öµòÁ¦ÀÇ ¿Ê(=GABERDINE)
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GABA an amino acid that is found in the central nervous system
GABA a loose coverall (coat or frock) reaching down to the ankles
GABA (usually in the plural) trousers
GABA a firm durable fabric with a twill weave
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