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Feulgen stain <technique> A selective cytochemical reaction for DNA in which sections or cells are first hydrolyzed with hydrochloric acid to produce apurinic acid and then are stained with Schiff's reagent to produce magenta-stained nuclei; generally the concentration of DNA in nucleoli and mitochondria is too low to permit detection by this stain
See: Kasten's fluorescent Feulgen stain.
(05 Mar 2000)
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Kasten's fluorescent Feulgen stain <technique> A fluorescent modification of the Feulgen stain, utilizing any one of a variety of fluorescent basic dyes to which SO2 is added; the brilliant fluorescence makes this method unusually sensitive and adaptable to cytofluorometric quantification of DNA.
(05 Mar 2000)
Feulgen reaction <procedure> A specific staining procedure for DNA: mild acid hydrolysis makes the aldehyde group of deoxyribose available to react with Schiff's reagent to give a purple colour.
(18 Nov 1997)
Feulgen reagent <chemical> A staining substance which specifically stains DNA. Robert Feulgen, in 1914, used this stain to find out that DNA is the hereditary material in cells.
(09 Oct 1997)
Feulgen, Robert <person> German nucleic acid biochemist and cytochemist, 1884-1955.
First to detect DNA in cells by a specific cytochemical test.
(05 Mar 2000)
Abbott's stain <technique> Spores are stained blue with alkaline methylene blue; bodies of the bacilli become pink with eosin counterstain.
(05 Mar 2000)
aceto-orcein stain <technique> A stain used for chromosomes in air-dried or squashed cytologic material.
(05 Mar 2000)
acid-fast stain <technique> A staining technique used to determine the cell wall property of a microorganism. After stained with dye such as hot carbolfuschin, an acid-fast organism, (for example Mycobacterium species) will retain the colour in its cell wall after being washed with acid-alcohol.
(13 Nov 1997)
acid stain <technique> A dye in which the anion is the coloured component of the dye molecule, e.g., sodium eosinate (eosin).
(05 Mar 2000)
Ag-AS stain <technique> A stain for the acid protein component of nucleolar regions which are active or which were transcriptionally active in the preceding interphase; uses silver nitrate, ammoniacal silver, and formalin.
Synonym: Ag-AS stain.
(05 Mar 2000)
Albert's stain <technique> A stain for diphtheria bacilli and their metachromatic granules; contains toluidine blue, methyl green, glacial acetic acid, alcohol, and distilled water.
(05 Mar 2000)
Altmann's anilin-acid fuchsin stain <technique> A mixture of picric acid, anilin, and acid fuchsin which stains mitochondria crimson against a yellow background.
(05 Mar 2000)
auramine O fluorescent stain <technique> A rapid and accurate technique for Mycobacterium tuberculosis, using auramine O-phenol and a methylene blue counterstain.
(05 Mar 2000)
basic fuchsin-methylene blue stain <technique> A stain for intact epoxy sections; semi-thick sections of plastic-embedded tissues have nuclei stained purple; collagen, elastic lamina, and connective tissue are stained blue; mitochondria, myelin, and lipid droplets are stained red; cytoplasm, smooth muscle cells, axoplasm, and chrondroblasts are stained pink.
(05 Mar 2000)
basic stain <technique> A dye in which the cation is the coloured component of the dye molecule that binds to anionic groups of nucleic acids (PO4&equiv;) or acidic mucopolysaccharides (e.g., chondroitin sulfate).
(05 Mar 2000)
Bauer's chromic acid leucofuchsin stain <technique> A stain for glycogen and fungi utilizing chromic acid as an oxidizing agent of polysaccharides, followed by Schiff's reagent; glycogen and fungi cell walls appear deep red.
(05 Mar 2000)
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