| MF | magnetic field; meat free; medium frequency; megafarad; membrane filler; merthiolate-formaldehyde [s... |
|---|---|
| FAB classification | French, American, British classification |
| FAB | fast atom bombardment; formalin ammonium bromide; fragment, antigen-binding [of immunoglobulins]; Fr... |
| Fab | fragment, antigen-binding [of immunoglobulins] |
| FAB | Fast Atom Bombardment |
|---|---|
| FAB-MS | Fast Atom Bombardment Mass Spectrometry |
| FAB MS | Fast Atom Bombardment Mass Spectroscopy |
| F 1+2 | fragments 1+2 |
| FAB | French American British |
| Okazaki fragments | Short fragments of newly synthesised DNA strands produced during DNA replication. All the known DNA polymerases can only synthesis DNA in one direction, the 5' to 3' direction. However as the strands separate, replication forks will be moving along one parental strand in the 3' to 5' direction and 5' to 3' on the other parental strand. On the former, the leading strand, DNA can be synthesised continuously in the 5' to 3' direction. On the other, the lagging strand, DNA synthesis can only occur when a stretch of single stranded DNA has been exposed and proceeds in the direction opposite to the movement of the replication fork (still 5' to 3). It is thus discontinuous and the series of fragments are then covalently linked by ligases to give a continuous strand. Such fragments were first observed by Okazaki using pulse labelling with radioactive thymidine. In eukaryotes, Okazaki fragments are typically a few hundred nucleotides long, whereas in prokaryotes they may contain several thousands of nucleotides. (18 Nov 1997) |
|---|---|
| immunoglobulins, fab | Antigen-binding fragments composed of one entire light chain and about half of one of the heavy chains, linked to each other by disulfide bonds. Fab contains the antigen binding site which is part of the variable region of the immunoglobulin molecule. (12 Dec 1998) |
| Fab | <immunology> Fragment of immunoglobulin prepared by papain treatment. Fab fragments (45 kD) consist of one light chain linked through a disulphide bond to a portion of the heavy chain and contain one antigen binding site. They can be considered as univalent antibodies. (18 Nov 1997) |
| FAB classification | <haematology> The classification of acute myeloid leukaemia on the basis of bone marrow and peripheral blood features. M0: Acute myeloid leukaemia with minimal evidence of myeloid differentiation. M1: Acute myeloblastic leukaemia. M2: Acute myeloblastic leukaemia with differentiation. M3: Acute promyelocytic leukaemia. M4: Acute myelomonocytic leukaemia. M5: Acute monocytic leukaemia. M6: Acute erythroleukaemia. M7: Acute megakaryocytic leukaemia. Acronym: FAB (07 Apr 1998) |
| Fab fragment | The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain. Synonym: Fab piece. (05 Mar 2000) |
| Fab piece | The antigen-binding fragment of an immunoglobulin molecule, consisting of both a light chain and part of a heavy chain. Synonym: Fab piece. (05 Mar 2000) |
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