| estrogen | <endocrinology, hormone> A generic term for oestrus producing steroid compounds, the female sex hormones. In humans, oestrogen is formed in the ovary, possibly the adrenal cortex, the testis and the foetoplacental unit, it has various functions in both sexes. It is responsible for the development of the female secondary sex characteristics and during the menstrual cycle it acts on the female genitalia to produce an environment suitable for the fertilization, implantation and nutrition of the early embryo. Oestrogen is used in oral contraceptives and as a palliative in cancer of the breast after menopause and cancer of the prostate, other uses include the relief of the discomforts of menopause, inhibition of lactation and treatment of osteoporosis, threatened abortion and various functional ovarian disorders. (18 Nov 1997) |
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| estrogen 2-hydroxylase | <enzyme> Same enzyme for hydroxylation in 2 or 4 position Registry number: EC 1.14.99.- Synonym: estrogen 4-hydroxylase, ethinylestradiol 2-hydroxylase (26 Jun 1999) |
| gene rearrangement, alpha-chain T-cell antigen receptor | Ordered rearrangement of T-cell variable gene regions coding for the alpha-chain of antigen receptors. (12 Dec 1998) |
| genes, T-cell receptor alpha | DNA sequences encoding the alpha chain of the T-cell receptor. The genomic organization of the tcr alpha genes is essentially the same in all species and is similar to the organization of ig genes. (12 Dec 1998) |
| alpha, alpha-phosphotrehalase | <enzyme> Forms glucose plus glucose-6-phosphate Registry number: EC 3.2.1.93 Synonym: trehalose-6-phosphate hydrolase, phospho-alpha(1,1)glucosidase, trea gene product, trec gene product (26 Jun 1999) |
| alpha,alpha-trehalose phosphorylase | <enzyme> Chemical name: alpha-d-glucopyranosyl-alpha-d-glucopyranose orthophosphate glucosyltransferase Registry number: EC 2.4.1.64 Synonym: trehalose phosphorylase (26 Jun 1999) |
| alpha-dextrin endo-1,6-alpha-glucosidase | <enzyme> An enzyme with action similar to that of isoamylase; it cleaves 1,6-alpha-glucosidic linkages in pullalan, amylopectin, and glycogen, and in alpha-and beta-amylase limit-dextrins of amylopectin and glycogen. Compare: isoamylase. Synonym: limit dextrinase, pullulanase, R enzyme. (05 Mar 2000) |
| alpha-hydroxymethyl-alpha'-(N-acetylaminomethylene)succinic acid hydrolase | <enzyme> Involved in degradation of vitamin b6; forms acetic acid plus ammonia plus carbon dioxide plus alpha-hydroxymethyl-succinic monoaldehyde Registry number: EC 3.5.1.- Synonym: compound b hydrolase (26 Jun 1999) |
| cholesterol-5 alpha,6 alpha-epoxide hydrase | <enzyme> Aspect of epoxide hydrolase, EC 3.3.2.3 Pharmacological action: carcinogen Registry number: EC 3.3.2.- Synonym: cholesterol epoxide hydrase, cholesterol epoxide hydrolase (26 Jun 1999) |
| CMP-acetylneuraminate-alpha-N-acetylneuramide alpha-2,8-sialyltransferase | <enzyme> Forms ganglioside gd3 Registry number: EC 2.4.99.8 Synonym: cmp-n-acetylneuraminate-gm3 sialyltransferase, gm3-sialosyltransferase, gd3 synthase, gd3-synthase, cmp-n-acetylneuraminate-(n-acetylneuraminyl)-d-galactosyl-d-glucosylceramide sialyltransferase, sialyltransferase II, st II, g(m3) alpha-2,8-sialyltransferase, st8sia I, stii enzyme, stiii enzyme, gt3 synthase (26 Jun 1999) |
| CMP-N-acetylneuraminate-alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase | <enzyme> Enzyme from foetal calf liver; forms branched tetrasaccharide, neuac-alpha2-3gal-beta1-3(neuac-alpha2-6)galnac of fetuin Registry number: EC 2.4.99.3 Synonym: cmp-aag-sialyltransferase, st6galnaci, galnac 2,6-sialyltransferase (26 Jun 1999) |
| NAD 3 alpha-hydroxy-5 alpha-pregnan-20-one-oxidoreductase | <enzyme> From rat liver microsomes Registry number: EC 1.1.1.- Synonym: nad-3-hp-20-oor (26 Jun 1999) |
| 1,4-alpha-d-glucan 6-alpha-d-glucosyltransferase | A glucosyltransferase that transfers an alpha-glucosyl residue in a 1,4-alpha-glucan to the primary hydroxyl group of glucose in a 1,4-alpha-glucan. See: 1,4-alpha-d-glucan branching enzyme. Synonym: oligoglucan-branching glycosyltransferase. (05 Mar 2000) |
| 1,4-alpha-glucan 6-alpha-glucosyltransferase | <enzyme> From aspergillus niger and oryzae Registry number: EC 2.4.1.24 (26 Jun 1999) |
| 15-hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic acid | <chemical> A stable prostaglandin endoperoxide analog which serves as a thromboxane mimetic. Its actions include mimicking the hydro-osmotic effect of vasopressin and activation of phospholipase c. Pharmacological action: vasoconstrictor agents. Chemical name: 5-Heptenoic Acid, 7-(6-(3-Hydroxy-1-Ocentyl)-2-Oxabicyclo(2.2.1)hept-5-yl)-, (1R-(1alpha,4alpha,5 beta(Z),6alpha(1E,3S*)))- (12 Dec 1998) |