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amyl valerate Isoamyl isovalerate;used as a sedative; formerly used in the treatment of gallstones because of its solvent action on cholesterol.
Synonym: apple oil.
(05 Mar 2000)
betamethasone 17-valerate <chemical> 9-fluoro-11 beta,17,21-trihydroxy-16 beta-methylpregna-1,4-diene-3,20-dione-17-valerate. A synthetic glucocorticoid with high topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.
Pharmacological action: steroidal anti-inflammatory agents, glucocorticoids, synthetic, glucocorticoids, topical.
Chemical name: Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-((1-oxopentyl)oxy)-, (11beta,16beta)-
(12 Dec 1998)
valerate <chemistry> A salt of valeric acid.
Source: Websters Dictionary
(01 Mar 1998)
acyl-CoA-estradiol-17-beta-acyltransferase <enzyme> Catalyses the esterification of estradiol with long chain fatty acids at the 17-position
Registry number: EC 2.3.1.-
Synonym: acylcoenzyme a-estradiol-17-beta-acyltransferase, estradiol 17-acyltransferase
(26 Jun 1999)
receptors, estradiol Cytoplasmic proteins that bind estradiol, migrate to the nucleus, and regulate DNA transcription.
(12 Dec 1998)
estradiol A hormone (272 D) synthesised mainly in the ovary, but also in the placenta, testis and possibly adrenal cortex. A potent oestrogen.
(18 Nov 1997)
estradiol 15 alpha-hydroxylase <enzyme> Catalyses the conversion of estradiol to 15alpha-hydroxyestradiol
Registry number: EC 1.14.99.-
Synonym: e15a-hydroxylase
(26 Jun 1999)
estradiol 16 alpha-hydroxylase <enzyme> Cyp2c11 is a male-specific cyp isoform
Registry number: EC 1.14.99.-
Synonym: 16 alpha-hydroxylase, estrone 16 alpha-hydroxylase, 16alpha-hydroxylase, steroid 16 alpha-hydroxylase, estrone 3-sulfate 16 alpha-hydroxylase, cytochrome p450cmf, cytochrome p450 2c, cytochrome p450iic11, cytochrome p450(ut-a), cytochrome p4502c-rml5, cytochrome p450h, cytochrome p450(male), cytochrome p4502c, cytochrome p450 2c3, cytochrome p450 2c9, oestrogen 16-hydroxylase, cyp2c3 gene product, cyp2c11 gene product, cytochrome p450 2c11, cyp 2d-9, cytochrome p450(tb), cyp2c9, cytochrome p-450(m1), cyp2c11
(26 Jun 1999)
estradiol-17 beta sulfotransferase <enzyme> Specific for estradiol 17beta; not the same as EC 2.8.2.15
Registry number: EC 2.8.2.-
(26 Jun 1999)
estradiol antagonists Compounds which inhibit or antagonise the biosynthesis or action of estradiol.
(12 Dec 1998)
estradiol benzoate unit The oestrogenic activity of 0.1 ug of a standard preparation of estradiol benzoate.
(05 Mar 2000)
estradiol dehydrogenases <enzyme> Enzymes that catalyze the oxidation of estradiol at the 17-hydroxyl group in the presence of NAD+ or NADP+ to yield estrone and NADH or NADPH. The 17-hydroxyl group can be in the alpha- or beta-configuration.2
Chemical name: Estradiol-17 beta:NAD(P)+ 17-oxidoreductase
Registry number: EC 1.1.1.62
(12 Dec 1998)
estradiol receptor tyrosine kinase <enzyme> Calcium and calmodulin dependent
Registry number: EC 2.7.1.-
Synonym: ertk
(26 Jun 1999)
ethinyl estradiol <chemical> (17 alpha)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol. A semisynthetic oestrogen with high oral oestrogenic potency. It is often used as the oestrogenic component in oral contraceptives.
Pharmacological action: antineoplastic agent, hormonal, oestrogens, synthetic.
Chemical name: 19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17alpha)-
(12 Dec 1998)
ethinyl estradiol-norgestrel combination <chemical> Ethinyl estradiol and norgestrel given in fixed proportions. It has proved to be an effective contraceptive.
Pharmacological action: contraceptives, oral, combined, contraceptives, oral, synthetic, contraceptives, postcoital, synthetic.
(12 Dec 1998)
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