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erythromycin <drug> An antibiotic that disrupts bacterial protein synthesis by binding totheir ribosomes and inhibiting translocation.
(09 Oct 1997)
erythromycin C-12 hydroxylase <enzyme> Required for the c-12 hydroxylation of the macrolactone ring in erythromycin synthesis; mw 44 kD; from saccharopolyspora erythraea; amino acid sequence given in first source
Registry number: EC 1.14.-
Synonym: hydroxylase eryk, eryk gene product, cytochrome p-450(eryk)
(26 Jun 1999)
erythromycin esterase <enzyme> Hydrolyzes the lactone ring of erythromycin
Registry number: EC 3.1.1.-
(26 Jun 1999)
erythromycin estolate <chemical> Lauryl sulfate salt of propionic ester of erythromycin. Found to cause jaundice. Essential hepatotoxic property is due to the propionyl ester linkage at the 2' position.
Pharmacological action: antibiotics, macrolide.
Chemical name: Erythromycin, 2'-propanoate, dodecyl sulfate (salt)
(12 Dec 1998)
erythromycin ethylsuccinate <chemical> Erythromycin, 2'-(ethyl butanedioate). An ester of erythromycin having the same antibacterial effect as erythromycin but with better absorption and fewer side effects.
Pharmacological action: antibiotics, macrolide.
Chemical name: Erythromycin, 2'-(ethyl butanedioate)
(12 Dec 1998)
erythromycin glucoheptonate A salt of the macrolide antibiotic, erythromycin.
(05 Mar 2000)
erythromycin propionate A salt of the macrolide antibiotic, erythromycin.
(05 Mar 2000)
erythromycin stearate A salt of the macrolide antibiotic, erythromycin.
(05 Mar 2000)
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S-adenosylmethionine-erythromycin O-methyltransferase <enzyme> Converts erythromycin c to erythromycin a in the presence of s-adenosylmethionine
Registry number: EC 2.1.1.-
Synonym: erythromycin o-methyltransferase
(26 Jun 1999)
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