| sarcoma, endometrial stromal | A highly malignant neoplasm of the endometrium, arising from the endometrial stroma. It represents one type of stromal tumour, the other being endolymphatic stromal myosis. They are differentiated on the basis of the number of mitoses per 10 high power fields: endometrial stromal sarcoma has 10 or more mitoses, endolymphatic stromal myosis fewer. Stroma sarcoma is seen most often between the ages of 45 and 50. (devita jr et al., cancer: principles & practice of oncology, 3d ed, p1146) (12 Dec 1998) |
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| endometrial stromal sarcoma | <tumour> A term sometimes used for a relatively rare sarcoma believed to be a form of endometriosis in which the lesions form multiple foci in the myometrium and in vascular spaces in other sites, and which consist of histologic and cytologic elements that resemble those of the endometrial stroma. Synonym: stromatosis. (05 Mar 2000) |
| sex cord-stromal tumour | A malignant neoplasm of the ovary or testis. These tumours differentiate toward sex cords (in embryonic gonads) in the form of female (i.e., granulosa and theca) cells, male (i.e., sertoli and leydig) cells, or indifferent elements. In the ovary, sex cord-stromal tumours comprise 5% of all ovarian neoplasms. In the testes, leydig and sertoli cell tumours comprise about 5% of all testicular neoplasms, 10% of which behave in a malignant fashion. (12 Dec 1998) |
| stromal | Stromatic; relating to the stroma of an organ or other structure. Synonym: stromic. (05 Mar 2000) |
| stromal cells | Connective tissue cells of an organ found in the loose connective tissue. These are most often associated with the uterine mucosa and the ovary as well as the haematopoietic system and elsewhere. (12 Dec 1998) |
| stromal hyperthecosis | Condition in which luteinised cells are present in ovarian stroma at a distance from follicular structures. (05 Mar 2000) |
| stromal processing peptidase | <enzyme> Involved in processing chloroplast stromal proteins Registry number: EC 3.4.24.- (26 Jun 1999) |
| ovarian stromal tumours | <radiology> Age 20 - 50 yrs, 20% of all ovarian tumours, fibroma / fibrosarcoma, granulosa-theca cell tumour, with or without oestrogens most likely to be precocious puberty, endometrial hyperplasia/carcinoma, fibrocystic breast disease, Sertoli-Leydig cell tumour, aka: arrhenoblastoma, with or without androgens most likely to be masculinization, may be mixed type (12 Dec 1998) |
| biopsy, endometrial | <investigation, procedure, surgery> A procedure by which a sample is taken of the endometrial lining of the uterus. This may be performed with or without an anaesthetic. Risks include bleeding after the procedure. This test is usually performed in the evaluation of abnormal menses, heavy menstruation or post-menopausal bleeding. It may be part of an infertility evaluation. Endometrial biopsy can reveal uterine cancer, uterine fibroids, uterine polyps and adenomyosis. Often performed in those with endometriosis as part of the evaluation. (21 Mar 1998) |
| endometrial | Relating to or composed of endometrium. (05 Mar 2000) |
| endometrial biopsy | <investigation, procedure, surgery> A procedure by which a sample is taken of the endometrial lining of the uterus. This may be performed with or without an anaesthetic. Risks include bleeding after the procedure. This test is usually performed in the evaluation of abnormal menses, heavy menstruation or post-menopausal bleeding. It may be part of an infertility evaluation. Endometrial biopsy can reveal uterine cancer, uterine fibroids, uterine polyps and adenomyosis. Often performed in those with endometriosis as part of the evaluation. (21 Mar 1998) |
| endometrial carcinoma | <oncology, tumour> A malignant cancer which arises from the cells which line the uterus. (27 Sep 1997) |
| endometrial cyst | A cyst resulting from endometrial implantation outside the uterus, as in endometriosis. (05 Mar 2000) |
| endometrial hyperplasia | <gynaecology, pathology> Thickening of the endometrial lining due to an overgrowth of mucosal cells. Symptoms often include irregular vaginal bleeding, heavy or prolonged menstrual cycles and post-menopausal bleeding in older women. Origin: Gr. Plassein = to form (07 Apr 1998) |
| endometrial implants | Fragments of endometrial mucosa implanted on pelvic structure following retrograde transference through the oviducts. (05 Mar 2000) |