| Edman, Pehr | <person> Australian scientist, 1916-1977. See: Edman method, Edman's reagent. (05 Mar 2000) |
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| edman degradation | A lab technique used to find out the order of amino acids in a polypeptide (chain of amino acids). It involves using the Edman reagent, phenyl isothiocyanate (PITC), to react one by one with each amino acid, in order. The technique is used in machines which automatically sequence (determine the order of subunits) polypeptides. (09 Oct 1997) |
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| Edman method | C6H5-N==C==S, a reagent that condenses with the free N-terminal amino group of a peptide chain to form a phenylthiohydantoin in the Edman method of identifying N-terminal amino acids. Synonym: Edman's reagent. Acronym: PITC (05 Mar 2000) |
| Edman reagent | Phenyl isothiocyanate. The classic method for sequence determination of peptides using sequential cleavage of the N terminal residue after reaction with Edman reagent. The N terminal amino acid is removed as a phenylthiohydantoin derivative. (18 Nov 1997) |
| Edman's reagent | C6H5-N==C==S, a reagent that condenses with the free N-terminal amino group of a peptide chain to form a phenylthiohydantoin in the Edman method of identifying N-terminal amino acids. Synonym: Edman's reagent. Acronym: PITC (05 Mar 2000) |