| gene products, rev | Trans-acting nuclear proteins whose functional expression are required for HIV viral replication. Specifically, the rev gene products are required for processing and translation of the HIV gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. Rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (car) in env, also known as the rev-responsive element (rre), is responsive to the rev gene product. Rev is short for regulator of virion. (12 Dec 1998) |
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| genes, rev | DNA sequences that form the coding region for a protein that regulates the expression of the viral structural and regulatory proteins in human immunodeficiency virus (HIV). Rev is short for regulator of virion. (12 Dec 1998) |
| rev | <molecular biology> A regulatory protein produced by HIV within infected cells. Rev helps transport HIV RNA sequences (messenger RNA) out from the nucleus into the cells cytoplasm, where it directs construction of proteins for new virus particles. (11 Jan 1998) |
| middle east | The countries of southwest asia and northeastern africa usually considered as extending from libya on the west to afghanistan on the east. (12 Dec 1998) |
| East African sleeping sickness | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| East African trypanosomiasis | A disease of humans caused by Trypanosoma brucei rhodesiense in eastern Africa from Ethiopia and Uganda south to Zimbabwe; it is clinically similar to Gambian trypanosomiasis but of shorter duration and more acute in form; patients suffer repeated episodes of pyrexia, become anaemic, and die commonly from cardiac failure. Synonym: acute African sleeping sickness, acute trypanosomiasis, East African sleeping sickness, East African trypanosomiasis. (05 Mar 2000) |
| East Coast fever | A serious disease of cattle in eastern and central Africa, caused by the protozoan Theileria parva and characterised by high fever, swelling of the lymph nodes, and high case fatality; transmitted by Rhipicephalus appendiculatus and other ticks of the genus Rhipicephalus. (05 Mar 2000) |
| far east | A geographic area of east and southeast asia encompassing china, hong kong, japan, korea, macao, mongolia, and taiwan. (12 Dec 1998) |
| Far East haemorrhagic fever | Tick-borne infection with Rickettsia sibirica, seen primarily in Siberia and Mongolia. (05 Mar 2000) |
| Far East Russian encephalitis | Tick-borne encephalitis (Eastern subtype). (05 Mar 2000) |