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early latent syphilis Infection with Treponema pallidum, the organism of syphilis, after the primary and secondary phases have subsided, during the first year after infection, before any manifestations of tertiary syphilis have appeared.
(05 Mar 2000)
early syphilis Primary, secondary, or early latent syphilis, before any tertiary manifestations have appeared.
(05 Mar 2000)
adenovirus early proteins <molecular biology, protein, virology> Proteins encoded by adenoviruses that are synthesised prior to, and in the absence of, viral DNA replication.
The proteins are involved in both positive and negative regulation of expression in viral and cellular genes, and also affect the stability of viral mRNA. Some are also involved in oncogenic transformation.
(12 Dec 1998)
cardiovascular syphilis Involvement of the cardiovascular system seen in late syphilis, usually resulting in aortitis, aneurysm formation, and aortic valvular insufficiency.
(05 Mar 2000)
genes, immediate-early Genes that show rapid and transient expression in the absence of de novo protein synthesis. The term was originally used exclusively for viral genes where immediate-early referred to transcription immediately following virus integration into the host cell. It is also used to describe cellular genes which are expressed immediately after resting cells are stimulated by extracellular signals such as growth factors and neurotransmitters.
(12 Dec 1998)
meningovascular syphilis A rare manifestation of secondary or tertiary syphilis characterised by mild, nonsuppurative, chronic inflammation of the leptomeninges and an intracranial or spinal angiitis.
(05 Mar 2000)
congenital syphilis <radiology> Wimberger sign, periostitis, part of ToRCHS complex
(12 Dec 1998)
primary syphilis The first stage of syphilis
See: syphilis.
(05 Mar 2000)
hereditary syphilis Synonym: congenital syphilis.
(05 Mar 2000)
history of medicine, early modern The period of the history of medicine from 1451 through 1600 a.d. History of medicine, 15th cent. And history of medicine, 16th cent. Are also available.
(12 Dec 1998)
secondary syphilis The second stage of syphilis
See: syphilis.
Synonym: mesosyphilis.
(05 Mar 2000)
nonvenereal syphilis Syphilis caused by organisms closely related to Treponema pallidum; spread by personal, but not necessarily venereal, contact; usually acquired in childhood, most common in areas of provery and overcrowding; rare in the United States; includes yaws, pinta and bejel.
Synonym: endemic syphilis.
(05 Mar 2000)
syphilis <microbiology> A sexually transmitted disease caused by the spirochete, Treponema pallidum. May also be acquired prenatally (foetal infection).
(27 Sep 1997)
syphilis, congenital Syphilis acquired in utero and manifested by any of several characteristic tooth (hutchinson's teeth) or bone malformations and by active mucocutaneous syphilis at birth or shortly thereafter. Ocular and neurologic changes may also occur.
(12 Dec 1998)
syphilis, cutaneous Cutaneous lesions arising from infection with treponema pallidum. In the primary stage, 18-21 days following infection, one or more chancres appear. If untreated, the subsequent stages of the disease appear as syphilids. These eruptions are superficial, nondestructive, exanthematic, transient, macular roseolas that may later be maculopapular or papular polymorphous or scaly, pustular, pigmented eruptions.(arnold, odom, and james, andrew's diseases of the skin, 8th ed, p409)
(12 Dec 1998)
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