| Donath-Landsteiner antibody |
var. Donath-Landsteiner test. [Julius Donath, Austrian physician, 1870?1950; Karl L. Landsteiner, Austrian-born U.S. biologist, 1868?1943] A test for paroxysmal hemoglobinuria. Blood from the patient is
Ãâó:
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| Donath-Landsteiner a. |
an IgG antibody directed against the P blood group antigen; it binds to red cells at low temperatures and induces complement-mediated lysis on warming, and is responsible for hemolysis in paroxysmal cold hemoglobinuria.
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| Donath-Landsteiner antibody, test |
see under antibody and test.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| Donath-Landsteiner t. |
(for paroxysmal cold hemoglobinuria): a test based on the fact that the blood of patients with this disease contains complement-dependent iso- and autohemolysin (Donath-Landsteiner antibody) which unites with red cells only at low temperatures (2° to 10°C), hemolysis occurring only after warming to 37°C.
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