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dihydroergotoxine <chemical> Dihydroergotoxine. A mixture of three different ergotaman-3',6',18-triones, dihydroergocornine, dihydroergocristine, and dihydroergocryptine. It has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The combination of the methanesulfonate salts of these alkaloids is dihydroergotoxine mesylate (see ergoloid mesylates).
Pharmacological action: adrenergic alpha-antagonists, dopamine agonists, neuroprotective agents, nootropic agents.
Chemical name: Ergotoxine, dihydro-
(12 Dec 1998)
dihydroergotoxine mesylate A mixture of dihydroergocornine methanesulfate, dihydroergocristine methanesulfate, and dihydroergocryptine methane sulfate; used as an alpha-adrenergic blocking agent for relief of cardiovascular insufficiency.
(05 Mar 2000)
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