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dexamethasone <drug> Steroid analogue (glucocorticoid), used as an anti-inflammatory drug.
(18 Nov 1997)
dexamethasone isonicotinate <chemical> 9-fluoro-11 beta,17,21-trihydroxy-16 alpha-methyl-pregna-1,4-diene-3,20-dione-21-isonicotinate. An anti-inflammatory, antiallergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. It may cause water and salt retention.
Pharmacological action: anti-allergic agents, steroidal anti-inflammatory agents, glucocorticoids, synthetic, glucocorticoids, topical.
Chemical name: Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-((4-pyridinylcarbonyl)oxy)-, (11beta,16alpha)-
(12 Dec 1998)
dexamethasone suppression test <endocrinology, investigation> A test that measures the response of the adrenal glands to ACTH.
Dexamethasone is given to the patient and then blood cortisol levels are measured. Under normal conditions, cortisol levels should drop in response to dexamethasone. In this test one milligram of dexamethasone is administered in the morning and then the blood is drawn for analysis the following morning.
Abnormal test results can indicate Cushing's syndrome.
(27 Sep 1997)
UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase <enzyme> Transfers n-acetylglucosamine 1-phosphate from udp-n-acetylglucosamine to dolichyl phosphate, forming n-acetylglucosaminylpyrophosphoryldolichol
Chemical name: udp-glcnac-dolichyl-phosphate glcnac-1-phosphate transerase
Registry number: EC 2.7.8.15
Synonym: n-acetylglucosamine-1-phosphate transferase, dol-p-p-glcnac synthase, dolichol pathway enzyme I, udp-acetylglucosamine-dolichol phosphate acetylglucosamine-1-phosphate transferase, glcnac-dp-1-phosphotransferase, udp-n-acetyl-d-glucosamine-dolichyl-phosphate n-acetyl-d-glucosaminephosphotransferase, dolichol-p-dependent n-acetylglucosamine-1-phosphate transferase, alg7 gene product
(26 Jun 1999)
UDP-GlcNAc-undecaprenyl phosphate N-acetylglucosaminyl 1-phosphate transferase <enzyme> Catalyses transfer of n-acetylglucosamine 1-phosphate from udp-glcnac to undecaprenyl phosphate
Registry number: EC 2.7.8.-
Synonym: glcnac-p-p-und synthase, gpt enzyme
(26 Jun 1999)
acetyl phosphate CH3CO-OPO32-;a "high energy" phosphate that acts as an acetate donor in the metabolism of various bacteria.
Synonym: acetic phosphoric anhydride.
(05 Mar 2000)
acidulated phosphate fluoride <chemical> Phosphoric acid, mixt. With sodium fluoride (naf). A sodium fluoride solution, paste or powder, which has been acidulated to pH 3 to 4 and buffered with a phosphate. It is used in the prevention of dental caries.
Pharmacological action: fluorides, topical.
Chemical name: Phosphoric acid, mixt. With sodium fluoride (NaF)
(12 Dec 1998)
acyl dihydroxyacetone phosphate oxidoreductase <enzyme> Forms acyl-sn-glycerol 3-phosphate; uses NADPH
Registry number: EC 1.1.1.-
(26 Jun 1999)
adenosine 3',5'-cyclic phosphate phosphodiesterase <enzyme> An enzyme that catalyses the hydrolysis of adenosine 3',5'-cyclic phosphate forming 5'-AMP. A crucial step in the regulation of cellular adenosine 3',5'-cyclic phosphate levels. Inhibited by caffeine.
Synonym: cAMP phosphodiesterase.
(05 Mar 2000)
adenosine 3'-phosphate 3'-Adenylic acid.
See: adenylic acid.
(05 Mar 2000)
adenosine 3'-phosphate 5'-phosphosulfate 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H.
Synonym: active sulfate.
Acronym: PAPS
(05 Mar 2000)
adenosine 5'-phosphate 5'-Adenylic acid.
See: adenylic acid.
(05 Mar 2000)
adenosine cyclic phosphate An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known.
Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate.
Acronym: cAMP
(05 Mar 2000)
alkyldihydroxyacetone phosphate acyltransferase <enzyme> Catalyses acylation of alkyl-dhap
Registry number: EC 2.3.1.-
Synonym: adapat
(26 Jun 1999)
alkyl dihydroxyacetone phosphate oxidoreductase <enzyme> Forms alkyl-sn-glycerol 3-phosphate, uses NADPH
Registry number: EC 1.1.1.-
(26 Jun 1999)
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