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desmoplastic 1. Causing or forming adhesions.
2. Causing fibrosis in the vascular stroma of a neoplasm.
(05 Mar 2000)
desmoplastic cerebral astrocytoma <tumour> A rare variant of astrocytoma most frequently occurring in infancy, the tumour has a spindled cell appearance.
(05 Mar 2000)
desmoplastic fibroma <tumour> A benign fibrous tumour of bone affecting children and young adults; cortical destruction may result.
(05 Mar 2000)
desmoplastic malignant melanoma <tumour> A melanoma with marked fibrosis surrounding atypical spindle-shaped melanocytes in the dermis.
(05 Mar 2000)
desmoplastic trichoepithelioma <tumour> A solitary, hard, annular, centrally depressed papule, occurring usually in women on the face, consisting of dermal strands of basaloid cells and small keratinous cysts within sclerotic desmoplastic stroma.
(05 Mar 2000)
desmoplastic tumours <radiology> Carcinoid of small bowel or colon, Hodgkin's lymphoma, scirrhous gastric carcinoma
(12 Dec 1998)
fibroma, desmoplastic A extremely rare bone tumour characterised by abundant collagen formation and a fibrous stroma, without evidence of mitosis or pleomorphism. It appears on X-rays as an osteolytic lesion with well-defined margins and must be differentiated from primary fibrosarcoma of bone. (devita jr et al., cancer: principles & practice of oncology, 3d ed, p1441)
(12 Dec 1998)
accelerated reaction A response occurring in a shorter time than expected; the cutaneous manifestations occurring during the period between the second and tenth day following smallpox vaccination; because it is intermediate between a primary reaction and an immediate reaction, it is regarded as evidence of some degree of resistance.
Synonym: vaccinoid reaction.
(05 Mar 2000)
acid reaction Any test by which an acid reaction is recognised such as the change of blue litmus paper to red, an excess of hydrogen ions over hydroxide ions in aqueous solution indicated by a pH value less than 7 (at 22°C).
Compare: dissociation constant of water.
(05 Mar 2000)
acute-phase reaction <immunology, rheumatology> Refers to the changes in synthesis of certain proteins within the serum during an inflammatory response, which provides rapid protection for the host against microorganisms via non-specific defense mechanisms.
It consists of fever, an increase in inflammatory humoral factors, and an increased synthesis by hepatocytes of a number of proteins or glycoproteins usually found in the plasma; the reaction is mediated by endogenous pyrogens, the hypothalamus, adrenal hormones, and other factors.
(12 Jul 2000)
acute situational reaction An acute emotional reaction related to extreme environmental stress.
Synonym: acute situational reaction.
(05 Mar 2000)
acute stress reaction A sudden bout of anxiety that is often accompanied by the features of hyperventilation (tingling around mouth and in fingertips, rapid breathing, faintness or fainting).
(27 Sep 1997)
addition reaction <chemistry> Any reaction in which two chemicals combine to form a single chemical.
(15 Jan 1998)
adverse drug reaction reporting systems Systems developed for collecting reports from government agencies, manufacturers, hospitals, physicians, and other sources on adverse drug reactions.
(12 Dec 1998)
adverse reaction Any undesirable or unwanted consequence of a preventive, diagnostic, or therapeutic procedure or regimen.
(05 Mar 2000)
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