| 영문 | deoxyribonucleic acid (DNA) | 한글 | 데옥시리보핵산 |
|---|---|---|---|
| 설명 | 핵산의 일종으로 DNA라고도 한다. Deoxyribonucleotide의 중합체이며 유전자의 화학적 본체이다. RNA바이러스 이외의 모든 생물은 DNA를 유전자로 지니고 있다. 디옥시리보뉴클레오티드(deoxyribonucleotide)는 염기와 당(2'-deoxy-D-ribose)과 인산으로 이루어진다. 염기는 아데닌(adenine), 구아닌(guanine), 티민(thymine)및 시토신(cytosine)의 4가지이며, 이것은 당에 부착되어 있다. 인산 역시 당의 한 부분에 부착되어 있다. 이 deoxyribonucleotide의 당은 다른 deoxy- ribonucleotide의 당과 인산을 사이에 놓고 결합을 하게 되어 하나의 긴 사슬을 형성하게 된다. 즉 당과 인산이 주축이 되어서 deoxyribonucleotide의 긴 사슬을 만든다. 이 deoxyribonucleotide의 사슬 두 개는 각각 deoxyribonucleotide에 부착되어 있는 염기들이 결합을 하여 두 개의 사슬이 결합되어 있는 이중나선 구조를 만들게 된다. 4가지 염기 아데닌은 티민과 결합을 하고, 시토신과 결합을 하게 된다. 즉 당과 인산은 긴 사슬을 만드는 역할을 하고 긴 사슬에 부착된 염기들의 결합에 의해서 두 개의 긴 사슬은 서로 붙어서 이중나선 구조를 만든다. DNA의 유전정보는 염기에 저장된다. 4개의 염기의 조합과 배열이 유전정보를 보관하는 하나의 암호 역할을 행하게 된다. |
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| 영문 | DNA | 한글 | 디옥시리보핵산, 디엔에이 |
|---|---|---|---|
| 설명 | Deoxyribonucleic acid의 약어. 데옥시리보스를 구성성분으로 하는 핵산. 유전자의 화학적 본태로서 염색체에 존재한다. 데옥시리보스에 유기염기와 인산이 결합한 뉴클레오티드(구성단위)가 포스포디에스테르결합에 의해 긴사슬 중합체를 형성하며, 두 개의 긴사슬이 서로 비틀려 꼬인 나선구조를 취한다. 디옥시리보뉴클레오티드(deoxyribonucleotide)는 염기와 당(2'-deoxy-D-riboe)과 인산으로 이루어진다. 염기는 아데닌(adenine), 구아닌(guanine), 티민(thymine) 및 시토신(cytosine)의 네가지이며, 이것은 당에 부착되어 있다. 인산 역시 당의 한 부분에 부착되어 있다. 이 디옥시리보뉴클레오티드의 당은 다른 디옥시리보뉴클레오티드의 당과 인산을 사이에 놓고 결합하게 되어 하나의 긴 사슬을 형성하게 된다. |
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| HLA | Human Leukocyte Antigen; 인백혈구 항원 ? HLA B27 Ag (+)로 나오는 경우... |
|---|---|
| KIPS | key indicators, probes, and scoring method [for evaluating compliance with requrements for accredita... |
| CREG | Cross REactive Group (of HLA Antigens) |
| HLA | histocompatibility leukocyte antigen; histocompatibility locus antigen; homologous leukocyte antibod... |
| HLA-LD | human lymphocyte antigen-lymphocyte defined |
| b-DNA | Branched DNA |
|---|---|
| DNA MTase | DNA methytransferase |
| DNA-MG | DNA Malignancy Grade |
| DNA-PK | DNA dependent protein kinase |
| DNA P | DNA polymerase |
IGF-II : insulin like growth factor-II의 약자. 많은 장기와 조직에 작용하여 단백 합성과 DNA, RNA의 합성을 증가시켜 세포의 수와 양을 증가
| DNA probes, HLA | DNA probes specific for the human leukocyte antigen genes, which represent the major histocompatibility determinants in humans. The four known loci are designated as a, b, c, and d. Specific antigens are identified by a locus notation and number, e.g., HLA-a11. The inheritance of certain HLA alleles is associated with increased risk for certain diseases (e.g., insulin-dependent diabetes mellitus). (12 Dec 1998) |
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| DNA probes | Species- or subspecies-specific DNA (including complementary DNA (DNA, complementary), conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridises with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32p and 125i and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections. (12 Dec 1998) |
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| DNA probes, HPV | DNA probes specific for the identification of human papilloma virus. (12 Dec 1998) |
| RNA probes | RNA, usually prepared by transcription from cloned DNA, which complements a specific mRNA or DNA and is generally used for studies of virus genes, distribution of specific RNA in tissues and cells, integration of viral DNA into genomes, transcription, etc. Whereas DNA probes are preferred for use at a more macroscopic level for detection of the presence of DNA/RNA from specific species or subspecies, RNA probes are preferred for genetic studies. Conventional labels for the RNA probe include radioisotope labels 32p and 125i and the chemical label biotin. RNA probes may be further divided by category into plus-sense RNA probes, minus-sense RNA probes, and antisense RNA probes. (12 Dec 1998) |
| molecular probes | A group of atoms or molecules attached to other molecules or cellular structures and used in studying the properties of these molecules and structures. Radioactive DNA or RNA sequences are used in molecular genetics to detect the presence of a complementary sequence by molecular hybridization. (12 Dec 1998) |
| nucleic acid probes | Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies. (12 Dec 1998) |
| oligonucleotide probes | Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridises with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32p and 125i and the chemical label biotin. (12 Dec 1998) |
| DNA-directed DNA polymerase | <enzyme> DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. Chemical name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) Registry number: EC 2.7.7.7 (12 Dec 1998) |
| HLA | <immunology> A genetic fingerprint on white blood cells and platelets, composed of proteins that play a critical role in activating the bodys immune system to respond to foreign organisms. Acronym: HLA (16 Dec 1997) |
| HLA-a1 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the a locus on chromosome 6. Individuals bearing this allele are more susceptible to hodgkin's disease. HLA-a1 is in linkage disequilibrium with HLA-b8 and HLA-dr3. (12 Dec 1998) |
| HLA-a2 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the a locus on chromosome 6. The HLA-a2 antigen is associated with recognition of the influenza a virus. (12 Dec 1998) |
| HLA-a3 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the a locus on chromosome 6. The allele occurs with increased frequency in individuals with idiopathic haemochromatosis. HLA-a3 is in linkage disequilibrium with HLA-b7 and HLA-dr2. (12 Dec 1998) |
| HLA-a antigens | <immunology> Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. at least 20 antigens have been identified which are encoded by the a locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts. (12 Dec 1998) |
| HLA antigens | <immunology> A complex family of genetically inherited proteins which are found on the surface of cells throughout the body. They determine the match between patient and potential donor in bone marrow transplantation. These factors are inherited from the mother and father and so the chance of having the same HLA antigens between siblings is 1 in 4. See: human lymphocyte antigens. (20 Jun 2000) |
| HLA-b27 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the b locus on chromosome 6. It is strongly associated with acute anterior uveitis, ankylosing spondylitis, and reiter's disease. Increased frequency of antigen in: ankylosing spondylitis (90%), Reiter syndrome (90%), enteropathic arthritis (75%), psoriatic arthritis (60%) normal frequency: white: 8%, black: 4% (12 Dec 1998) |
| HLA-b35 antigen | <immunology> Human histocompatibility (HLA) surface antigen encoded by the b locus on chromosome 6. It is weakly associated with a number of diseases. (12 Dec 1998) |
Synonyms : HLA-A DNA Probes, HLA-B DNA Probes, HLA-C DNA Probes, HLA-D DNA Probes, HLA-DR DNA Probes, HLA-Dw DNA Probes, DNA Probes, HLA-A, DNA Probes, HLA-B, DNA Probes, HLA-C, DNA Probes, HLA-D, DNA Probes, HLA-DR, DNA Probes, HLA-Dw, HLA A DNA Probes, HLA B DNA Probes
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
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