| DNA nucleotidyltransferases | <enzyme> A general term denoting enzymes that catalyze the template-directed incorporation of deoxyribonucleotides into a DNA chain. Registry number: EC 2.7.7.- (12 Dec 1998) |
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| gentamicin 2''-nucleotidyltransferase | <enzyme> Chemical name: aminoglycoside 2''-adenylyltransferase Registry number: EC 2.7.7.46 Synonym: gentamycin adenylase, gentamycin adenylyltransferase, aminoglycoside adenylyltransferase, aminoglycoside 2''-o-nucleotidyltransferase, 2''-o-adenylyltransferase, aada2 gene product (26 Jun 1999) |
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| polyribonucleotide nucleotidyltransferase | <enzyme> An enzyme of the transferase class that catalyses the reaction RNA(n+1) and orthophosphate to yield RNA(n) and a nucleoside diphosphate, or the reverse reaction. ADP, idp, GDP, udp, and cdp can act as donors in the latter case. Chemical name: Polyribonucleotide:orthophosphate nucleotidyltransferase Registry number: EC 2.7.7.8 (12 Dec 1998) |
| tRNA nucleotidyltransferase | <enzyme> EC 2.7.7.21 (trna cytidylyltransferase) and EC 2.7.7.25 (trna adenylyltransferase) may be identical Registry number: EC 2.7.7.- Synonym: ctp(ATP)-trna nucleotidyltransferase, trna adenylyltransferase, trna cytidylyltransferase, ATP(ctp)-trna nucleotidyltransferase, transfer RNA nucleotidyltransferase, cca-adding enzyme (26 Jun 1999) |
| kanamycin nucleotidyltransferase | <enzyme> From plasmid pub110-carrying cells of b. Subtilis Registry number: EC 2.7.7.- (26 Jun 1999) |
| lincosaminide O-nucleotidyltransferase | <enzyme> From staphylococcus; forms lincomycin 3-(5'-adenylate) and clindamycin 4-(5'-adenylate) Registry number: EC 2.7.7.- Synonym: lincomycin 3-o-nucleotidyltransferase, clindamycin 4-o-nucleotidyltransferase, li-n-transferase, lin enzyme (26 Jun 1999) |
| DNA-directed DNA polymerase | <enzyme> DNA-dependent DNA polymerases found in bacteria, animal and plant cells. During the replication process, these enzymes catalyze the addition of deoxyribonucleotide residues to the end of a DNA strand in the presence of DNA as template-primer. They also possess exonuclease activity and therefore function in DNA repair. Chemical name: Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed) Registry number: EC 2.7.7.7 (12 Dec 1998) |
| A-DNA | A form of DNA in which the helix is right-handed and the overall appearance is short and broad. (05 Mar 2000) |
| a-form DNA | <molecular biology> One of several forms that can be assumed by a double helix. A-DNA is stable in dehydrated conditions. This form is less common than the dominant form found under physiological conditions -- beta-DNA. This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA. (09 Oct 1997) |
| antisense DNA | <molecular biology> A synthetic DNA strand that is complementary to a particular strand of target DNA with a complementary sequence of bases. This results in preventing expression of the gene encoded. These proteins can be used to selectively turn off production of certain proteins or block viral genetic instructions, by marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. (14 Nov 1997) |
| apurinic DNA | <molecular biology> A DNA molecule that has lost adenine and guanine, its purine bases. Apurinic DNA can be produced by treating the DNA with acid. (09 Oct 1997) |
| ATP-dependent DNA strand transferase | <enzyme> From human cell nuclei; catalyses strand exchange between homologous DNA sequences; magnesium dependent, requires ATP hydrolysis Registry number: EC 2.7.7.- Synonym: ATP-dep-DNA-str trnsfase (26 Jun 1999) |
| bacteriophage T7 induced DNA polymerase | <enzyme> Complex of two proteins, phage gene 5 protein and E coli thioredoxin Registry number: EC 2.7.7.- Synonym: t7 phage DNA polymerase, sequenase, t7 DNA polymerase, thermo sequenase (26 Jun 1999) |
| base in DNA | A unit of the DNA. There are 4 bases: adenine (A), guanine (G), thymine (T), and cytosine (C). The sequence of bases (for example, CAG) is the genetic code. (12 Dec 1998) |
| beta-DNA | <molecular biology> The normal form of DNA found in organisms, which exists as a right-handed helix. (09 Oct 1997) |
| blunt-end DNA | <molecular biology> A fragment of a DNA molecule in which the ends of both strands are even with each other rather than one strand being longer than the other. (09 Oct 1997) |