DNA Res : KMLE 의학 검색 엔진 - 의학사전, 의학용어, 의학약어, 의학논문, 약품/의약품 검색

MeSH(Medical Subject Headings) 맞춤 검색 (http://www.nlm.nih.gov) 결과 : 2 페이지: 1

DNA Restriction Enzymes - 새창 Enzymes that are part of the restriction-modification systems. They catalyze the endonucleolytic cleavage of DNA sequences which lack the species-specific methylation pattern in the host cell's DNA. Cleavage yields random or specific double-stranded fragments with terminal 5'-phosphates. The function of restriction enzymes is to destroy any foreign DNA that invades the host cell. Most have been studied in bacterial systems, but a few have been found in eukaryotic organisms. They are also used as tools for the systematic dissection and mapping of chromosomes, in the determination of base sequences of DNAs, and have made it possible to splice and recombine genes from one organism into the genome of another. EC 3.21.1.
Synonyms : DNA Restriction Enzyme, Restriction Endonuclease, Endonuclease, Restriction, Endonucleases, Restriction, Enzymes, DNA Restriction, Restriction Enzyme, DNA, Restriction Enzymes, DNA
DNA Restriction-Modification Enzymes - 새창 Systems consisting of two enzymes, a modification methylase and a restriction endonuclease. They are closely related in their specificity and protect the DNA of a given bacterial species. The methylase adds methyl groups to adenine or cytosine residues in the same target sequence that constitutes the restriction enzyme binding site. The methylation renders the target site resistant to restriction, thereby protecting DNA against cleavage.
Synonyms : DNA Restriction Modification Enzymes, Restriction Modification Systems, Enzymes, DNA Restriction-Modification, Modification Systems, Restriction, Restriction-Modification Enzymes, DNA, Systems, Restriction Modification, Systems, Restriction-Modification