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DD-carboxypeptidase-endopeptidase <enzyme> Hydrolyzes c-terminal d-ala-d-peptide, where second amino acid can vary
Registry number: EC 3.4.15.-
Synonym: dacf protein
(26 Jun 1999)
ddc <drug> A nucleoside analogue that inhibits infection of new cells by HIV.
It is FDA-approved for the treatment of HIV when used in combination with AZT in patients with CD4 cell counts below 300 who have deteriorated despite treatment and as monotherapy following AZT-failure.
Possible side effects include nerve damage in the hands and feet (peripheral neuropathy) and sores in the mouth.
(09 Oct 1997)
ddd <chemical> An organochlorine insecticide that is slightly irritating to the skin. (from merck index, 11th ed, p482)
Pharmacological action: insecticide, organochlorine.
Chemical name: Benzene, 1,1'-(2,2-dichloroethylidene)bis(4-chloro-
(12 Dec 1998)
dde <chemical> An organochlorine pesticide, it is the ethylene metabolite of ddt.
Pharmacological action: insecticide, organochlorine.
Chemical name: Benzene, 1,1'-(dichloroethenylidene)bis(4-chloro-
(12 Dec 1998)
ddl <drug> A nucleoside analogue that inhibits infection of new cells by HIV.
FDA-approved for individuals intolerant to or failing on AZT and for people who have taken AZT for sixteen weeks or more.
Side effects can include nerve damage in the hands and feet (peripheral neuropathy), damage to the pancreas (pancreatitis) and diarrhoea.
(09 Oct 1997)
DDT <chemical> This chlorinated organic insecticide was discovered by Swiss chemist Paul Muller in 1939.
DDT has been especially useful in controlling mosquitos that carry malaria, but some strains of the insects have become resistant to it. DDT has comparatively low acute toxicity in humans (it is thought to cause cancer), but it persists for a longtime in the environment and is disastrously toxic to birds, especially top-level predators such as hawks and eagles.
The chemical interferes with the birds ability to metabolise calcium, and thus affected birds that lay eggs with fatally thin shells. DDT has been banned in most countries, but it is still widely used on crops in Latin America.
(09 Oct 1997)
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