| 영문 | cystic fibrosis | 한글 | 낭성섬유증 |
|---|---|---|---|
| 설명 | 유전병의 하나로 땀샘, 기관지에서 점액을 분비하는 샘, 이자등의 외분비샘(몸 밖으로 액체를 분비하는 샘. 내분비샘을 제외한 모든 샘을 이른다)의 이상을 특징으로 하는 병이다. 중요한 병적인 변화는 주로 기관지에서 점액을 분비하는 분비샘에서 지나치게 점도가 높은 점액이 분비되어 기관지를 막아 호흡장애를 일으키는 폐의 병터이며, 땀에서 과도한 전해질 특히 염화나트륨(NaCl)이 분비되어 몸에 전해질이 부족하게 된다. 또 이자의 소화액을 분비하는 분비샘의 이상으로 이자관이 막히거나 이자의 기능이 떨어져서 소화의 장애를 일으키기도 한다. 유태계에 많으며 우리나라에는 아주 드물다. |
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| 영문 | fibrosis | 한글 | 섬유증, 섬유화 |
|---|---|---|---|
| 설명 | 아교질섬유를 형성하는 섬유조직의 증식으로 몸의 실질세포의 괴사나 손상에 이어서 나타나는 경우가 보통이다. 두 단계, 즉 손상부위에서 섬유모세포의 이주와 증식, 그리고 섬유모세포에 의한 세포의 바탕질 축적으로 진행된다. 피부의 경우 진피내 섬유모세포의 증식과 아교질 섬유의 증식이 있는 경우를 섬유화, 거의 아교질 섬유로만 구성되는 경우를 경화라고 한다. |
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| CFF | critical flicker fusion [test]; critical fusion frequency; cystic fibrosis factor; Cystic Fibrosis F... |
|---|---|
| CFP | chronic false positive; Clinical Fellowship Program; cyclophosphamide, fluorouracil, prednisone; cys... |
| MF | 1) Myelo-Fibrosis = Agnogenic Myeloid Metaplasia with Myelo-F... |
| IPF | idiopathic pulmonary fibrosis; infection-potentiating factor; interstitial pulmonary fibrosis |
| CF | 1) Cystic Fibrosis 2) Complement Fixing antibody 3) Conver... |
| CFTR | Cystic Fibrosis Transmembrane Conductance Regulator |
|---|---|
| CFTR | Cystic Fibrosis Transmembrane Conductance Regulator Gene |
| CFTR | Cystic Fibrosis Transmembrane Regulator |
| CFP | Cystic fibrosis protein |
| CFTR | cystic fibrosis transmembrane conductance regulator protein |
| cystic fibrosis | <chest medicine> A generalised disorder of infants, children and young adults, in which there is widespread dysfunction of the exocrine glands, characterised by signs of chronic pulmonary disease (due to excess mucus production in the respiratory tract), pancreatic deficiency, abnormally high levels of electrolytes in the sweat and occasionally by biliary cirrhosis. There is an ineffective immunologic defense against bacteria in the lungs. Pathologically, the pancreas shows obstruction of the pancreatic ducts by amorphous eosinophilic concretions, with consequent deficiency of pancreatic enzymes, resulting in steatorrhoea and azotorrhoea and intestinal malabsorption. The degree of involvement of organs and glandular systems may vary greatly, with consequent variations in the clinical picture. Inheritance: autosomal recessive. (13 Nov 1997) |
|---|---|
| cystic fibrosis antigen | Now known to be MRP 8. See: calgranulins. (18 Nov 1997) |
| cystic fibrosis transmembrane conductance regulator | Gene believed to be defective in cystic fibrosis. Gene encodes a chloride channel, homologous to a family of proteins that actively transport small solutes in an ATP dependent manner (ABC transporters). The regulator protein is a protein which is embedded in the cell membrane and acts as a channel for certain ions to be transported into or out of the cell. The disease cystic fibrosis is caused by a defect in the gene for this protein. (09 Oct 1997) |
| other-directed | Pertaining to a person readily influenced by the attitudes of others. (05 Mar 2000) |
| transferases (other substituted phosphate groups) | <enzyme> A class of enzymes that transfers substituted phosphate groups. Registry number: EC 2.7.8 (12 Dec 1998) |
| amyloidosis: bone manifestations | <radiology> Joint pain without radiographic findings, osteoporosis, especially in axial skeleton, lytic lesions that destroy cortex and invade soft tissue, wrist, scaphoid and lunate lesions that may extend into the carpal tunnel, inducing the classic complaints of carpal tunnel syndrome amyloid arthropathy Differential diagnosis: pigmented villonodular synovitis, synovial chondromatosis, rheumatoid arthritis, TB (12 Dec 1998) |
| amyloidosis: gastrointestinal manifestations | <radiology> Oesophagus, loss of peristalsis, megaesophagus, stomach, small and rigid (simulate linitis plastica), effaced rugal pattern, diminished/absent peristalsis, may be localised to antrum, amyloidoma: well defined submucosal mass, small bowel, diffuse form (more common), diffuse, uniform thickening of valvulae conniventes, broadened flat undulated mucosal folds (mucosal atrophy), jejunalization of ileum, impaired motility, small bowel dilatation, localised form: multiple small deposits; associated with pseudoobstruction, colon, psudopolyps (12 Dec 1998) |
| rheumatoid arthritis: joint manifestations | <radiology> Early signs: fusiform periarticular soft tissue swelling (result of effusion), regional osteoporosis (disuse and local hyperaemia), widened joint space, marginal and central bone erosion (base of 4th proximal phalanx most common), change in ulnar styloid and distal radioulnar joint, atlantoaxial dislocation, giant synovial cysts late signs: flexion/extension contractures with ulnar subluxation/dislocation, destruction/fusion of joints, elevation of humeral heads (tear/atrophy of rotator cuff), resorption of distal clavicle, erosion of superior margins of posterior portions of 3-5th ribs, destruction/narrowing of disc spaces, destruction of zygapophyseal joints without osteophyte formation, resorption of spinous process, protrusio acetabuli (from osteoporosis) (12 Dec 1998) |
| crohn disease: extraintestinal manifestations | <radiology> Fatty liver, gallstones (28-34%), risk 3-5X higher than expected, secondary to malabsorption of bile salts in terminal ileum, correlation with length of diseased ileum and duration of disease, sclerosing cholangitis, bile duct carcinoma, amyloidosis, urolithiasis: oxalate/uric acid stones, migratory arthritis (5-20%), sacroilitis, ankylosing spondylitis, erythema nodosum, uveitis see: Crohn disease (12 Dec 1998) |
| sickle cell anaemia: bone manifestations | <radiology> 8-13% of blacks carry sickling factor, symptoms: chronic ulcers, pain crises, many infections, priapism X-ray findings: deossification due to marrow hyperplasia, decreased bone density in skull with widened diploe, H-shaped vertebrae or fish vertebrae, rib notching, thrombosis and infarction, avascular necrosis, especially femoral head, periosteal treatmentn (bone within bone), secondary osteomyelitis, Staph. Aureus greater than Salmonella, dactylitis = hand foot syndrome, growth effects, bone shortening secondary to diminished blood supply, death less than 40y (12 Dec 1998) |
| skin manifestations | Dermatologic disorders attendant upon non-dermatologic disease or injury. (12 Dec 1998) |
| skin manifestations of GI disease | <radiology> Pancreatic carcinoma . . . . . . . . Thrombophlebitis migrans, glucagonoma . . . . . . . . . Migratory necrolytic erythema, IBD . . . . . . . . . . . . . . . Pyoderma gangrenosum, sprue / coeliac disease. . . . Dermatitis herpetiformis, Whipple disease . . . . . . . Pigmentation, primary biliary cirrhosis . . . . Exanthemasma, hepatic cirrhosis . . . . . . . . Spider angiomata (12 Dec 1998) |
| neurologic manifestations | Neurologic disorders attendant upon non-neurologic disease or injury. (12 Dec 1998) |
| oral manifestations | Disorders of the mouth attendant upon non-oral disease or injury. (12 Dec 1998) |
| tuberculosis: gastrointestinal manifestations | <radiology> Ileocaecal area, most common site (80-90%), Stierlin sign, Fleischner sign, thickened ileocaecal valve, fissures, ulcers, sinus tracts, fistulas, perforation, colon, segmental involvement; especially on right side, ulcerating colitis with pseudopolyps, hourglass stricture, wall thickening, gastroduodenal area, simultaneous involvement of pylorus and duodenum, stenotic pylorus with gastric outlet obstruction, narrowed antrum (linitis plastica appearance), ulcers, thickened folds, antral fistula, oesophagus, least common site, ulcers, stricture, mass, sinus tracts (12 Dec 1998) |
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|
제품명 |
판매사 |
보험코드 | 성분/함량 | 구분/보험급여 |
|---|