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coumarin <drug> O hydroxycinnamic acid. Pleasant smelling compound found in many plants and released on wilting (probably a major component of the smell of fresh hay). Has anticoagulant activity by competing with Vitamin K.
(18 Nov 1997)
coumarin hydroxylase <enzyme> Different preparations hydroxylate at position 3 and position 7; if cytochrome p-450coh is mutated at position 209, its substrate specificity is changed from coumarin hydroxylation to steroid hydroxylation
Registry number: EC 1.14.99.-
Synonym: cytochrome p-450coh, cytochrome p-4502a-5, cyp2a-5 gene product, coumarin 7-hydroxylase, cytochrome p-450 2a6, cyp2a6, cytochrome p-450 2a3, cyp2a3, p450 2a5, dhea hydroxylase, cyp2a5
(26 Jun 1999)
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