Core Binding Factor alpha Subunits - ț̢
A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
Synonyms : Acute Myeloid Leukemia Proteins, PEBP2A Transcription Factors, Polyomavirus Enhancer A Binding Protein 2, Polyomavirus Enhancer Binding Protein 2, Alpha Subunit, Runt Domain Factor, Runx Proteins, Transcription Factors, PEBP2A